Compositions for treating herpes simplex virus infections

Drug – bio-affecting and body treating compositions – Dentifrices

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Details

424 54, A61K 716, A61K 722, A61K 31055, A61K 3114

Patent

active

058558721

ABSTRACT:
A composition for treating diseased tissues resulting from a herpes simplex virus infection. When in ointment form, the composition has dispersed in an oil and water emulsion two distinct antimicrobial agents, one being Triclosan which is non-cationic and water insoluble, the Triclosan being solubilized by a solubilizer. The second antimicrobial agent which is cationic and water-soluble, is combined with the solubilized Triclosan to produce an antimicrobial composite that is polar and retained by the diseased tissues to which it is applied.

REFERENCES:
patent: 5158699 (1992-10-01), MacGilip et al.
patent: 5236699 (1993-08-01), Libin
patent: 5328682 (1994-07-01), Pullen et al.
patent: 5348738 (1994-09-01), Takatsuka et al.
patent: 5362737 (1994-11-01), Vora et al.
patent: 5447923 (1995-09-01), Catrenich et al.
patent: 5500448 (1996-03-01), Cummins et al.
patent: 5503822 (1996-04-01), Schulman
patent: 5578315 (1996-11-01), Chien et al.
patent: 5607681 (1997-03-01), Garey et al.
Drug Launches Dentyl PH The Fresh Breath Company United Kingdom Jul. 1997--Liquid Oral Tropical: Cetylpyridinium CL, Trillosan, Mint Oil Clove Oil, Nov. 17, 1997.
Drug Launches Antebor-N So Dip Switzerland May 1995 Topical Antiacne Preparation for Acne Seboorone Chlorhexidine 0.3% Triclosan 0.69%, Aug. 21, 1995.
Drug Launches Hexacorton Cream Orva Turkey 3rd Qtr-1991 Topical Corticosteroid Combinations Prednisolone 21 Acetate 5% Triclosan 3% Chlorohexidine HCG 2%, Mar. 30, 1992.
Skaari et al Jl. Clin. Periodont. 23(8):778-781 Aug. 1996 "Mouthrinses Contains Tricosan Reduce the Incideme of Recurrent Aphthous Ulcers" (RAV).
Addy et al. Jl. Clin. Periodont. 4(5):108-116 Dec. 1977 "Hibitane in the Treatment of Aphthous Ulceration".

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