Compositions containing tris salt of cholesterol hemisuccinate a

Details Compositions containing tris salt of cholesterol hemisuccinate a Compositions containing tris salt of cholesterol hemisuccinate a

1989-10-23

1993-07-27

Lovering, Richard D.

Drug, bio-affecting and body treating compositions

Designated organic active ingredient containing

Having -c-, wherein x is chalcogen, bonded directly to...

424 11, 424 71, 424DIG15, 514887, 514967, A61K 31415

Patent

active

052311120

ABSTRACT:
Methods and compositions are described for the preparation of bioactive agents entrapped in lipid vesicles the bilayers of which comprise a salt form of an organic acid derivative of a sterol, such as the tris-salt form of a sterol hemisuccinate, and to bompositions comprising a mixture of tris(hydroxymethyl)aminomethane salt of cholesteryl hemisuccinate with either an antifungal compound or a peptide. These compositions have various applications in vivo.

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