Drug – bio-affecting and body treating compositions – Designated organic active ingredient containing – Having -c- – wherein x is chalcogen – bonded directly to...
Reexamination Certificate
2007-03-13
2007-03-13
Wilson, James O. (Department: 1624)
Drug, bio-affecting and body treating compositions
Designated organic active ingredient containing
Having -c-, wherein x is chalcogen, bonded directly to...
C514S303000, C544S284000, C546S119000
Reexamination Certificate
active
10795538
ABSTRACT:
This invention provides compounds that are useful for treating patients having a TGF-β-mediated disease, particularly an ALK5-mediated disease. The compounds are represented by formula I:wherein: a-b is CH2CH2, CH2CH2CH2, CH═CH, CH═N, or N═CH; Z is N or C—F; and G is C1-6aliphatic or a phenyl, naphthyl, or 5-6 membered heteroaryl ring.
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Chemical Abstracts Registry File, Registry No. 685134-74-1 (see attached).
Pandey Anjali
Scarborough Robert M.
Venkatraman Meenakshi S.
Millennium Pharmaceutical Inc.
Millennium Pharmaceuticals Inc.
Truong Tamthom N.
Wilson James O.
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