Compositions and methods for detecting human herpesviruses

Details Compositions and methods for detecting human herpesviruses Compositions and methods for detecting human herpesviruses

2004-12-30

2008-10-28

Horlick, Kenneth R. (Department: 1637)

Chemistry: molecular biology and microbiology

Measuring or testing process involving enzymes or...

Involving nucleic acid

C536S023100

Reexamination Certificate

active

07442505

ABSTRACT:
The present invention relates to primer compositions and methods for identifying and distinguishing CMV, EBV-A/B, HSV-1/2, HHV-6 and VZV herpesviruses in a sample.

REFERENCES:
Yamamoto et al. (“A single tube PCR assay for simultaneous amplification of HSV-1/2, VZV, CMV, HHV-6A/-6B, and EBV DNAs in cerebral fluid form patients with virus-related neurological diseases” Journal of NeuroVirology. 2000. 6: pp. 410-417).
Tsurumi et al. (“A Single-Base Change within the DNA Polymerase Locus of Herpes Simplex Virus Type 2 Can Confer Resistance to Aphidicolin” Journal of Virology. Feb. 1987. pp. 388-394).
Buck et al (“Design Strategies and Performance of Custom DNA Sequencing Primers” Biotechniques. 1999. 27(3): pp. 528-536).
GENBANK Accession No. AY038367 (Oct. 2002).
Tsurumi et al. (“A Single-Base Change within the DNA Polymerase Locus of Herpes Simplex Virus Type 2 Can Confer Resistance to Aphidicolin” Journal of Virology. Feb. 1987. pp. 388-394).
Buck et al (“Design Strategies and Performance of Custom DNA Sequencing Primers” Biotechniques. 1999. 27(3): pp. 528-536).
Stratagene (“Gene Characterization Kits” 1988).
Casas et al. (“Detection of enteroviral RNA and specific DNA of herpesviruses by multiplex genome amplification” J Virol Methods. Jun. 1997;66(1):39-50).
GENBANK Accession No. AF133604. Jul. 10, 2000.
GENBANK Accession No. HS2POLD. Aug. 2, 1993.
GENBANK Accession No. HH6DNAPOL. Aug. 23, 1995.
Pozo et al. (“Detection and typing of lymphotropic herpesviruses by multiplex polymerase chain reaction” J Virol Methods. Apr. 1999;79(1):9-19).
Elfath et al., “Multiplex PCR:Optimization and Application in Diagnostic Virology”, Clinical Microbiology Reviews 2000 13(4) :559-570.
Markoulatos et al., “Detection and Typing of HSV-1, HSV-2, and VZV by a Multiplex Polymerase Chain Reaction”, Journal of Clinical Laboratory Analysis 2000 14:214-219.
McElhinney et al., “Multiplex polymerase chain reaction for human herpesvirus-6, human cytomegalovirus, and human β-globin DNA”, Journal of Virological Methods 1995 53:223-233.
Cassinotti et al., “Suitability and Clinical Application of a Multiplex Nested PCR Assay for the Diagnosis of Herpes Simplex Virus Infections”, Journal of Medical Virology 1996 50:75-81.
Druce et al., “Utility of a Multiplex PCR Assay for Detecting Herpesvirus DNA in Clinical Samples”, Journal of Clinical Microbiology 2002 40 (5) :1728-1732.
O'Neill et al., “Real-Time Nested Multiplex PCR for the Detection of Herpes Simplex Virus Types 1 and 2 andVaricella zosterVirus”, Journal of Medical Virology 2003 71:557-560.
Read et al., “Laboratory Diagnosis of Common Viral Infections of the Central Nervous System by Using a Single Multiplex PCR Screening Assay”, Journal of Clinical Microbiology 1999 37 (5) :1352-1355.
Yamamoto et al., “A single tube PCR assay for simultaneous amplification of HSV-1/-2, VZV, CMV, HHV-6A/-6B, and EBV DNAs in cerebrospinal fluid from patients with virus-related neurological diseases”, Journal of NeuroVirology 2000 6:410-417.

Affiliated with

Also associated with

Rating

Compositions and methods for detecting human herpesviruses does not yet have a rating. At this time, there are no reviews or comments for this patent.

If you have personal experience with Compositions and methods for detecting human herpesviruses, we encourage you to share that experience with our LandOfFree.com community. Your opinion is very important and Compositions and methods for detecting human herpesviruses will most certainly appreciate the feedback.

Rate now

Comments { 0 }

Profile ID: LFUS-PAI-O-4006398