Composition and method for treatment of vaginal yeast infections

Drug – bio-affecting and body treating compositions – Designated organic active ingredient containing – Radical -xh acid – or anhydride – acid halide or salt thereof...

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514 31, 514396, 514399, 514252, 514738, A61K 31045, A61K 3170, A61K 31495, A61K 3150, A61K 31415, A61K 3119

Patent

active

053408365

ABSTRACT:
A composition for the treatment of vaginal yeast which promotes normal vaginal bacterial growth during treatment, comprising a yeast-inhibitory agent selected from one or more of the group consisting of ethylene glycol, propylene glycol, and glycerol, and an effectively buffered aqueous acetate solution, in which the concentration of acetate is effective to establish a pH of the composition in the range of from about 5 to about 7, the presence of unionized acetate inhibits yeast selectively compared to the bacteria, and the proportions of the yeast-inhibitory agent and the buffering solution are effective to allow the active yeast-inhibitory agent to inhibit the vaginal yeast Candida. A method of treatment of vaginal yeast while promoting normal vaginal bacterial growth, by intravaginal application of the composition described above, is also disclosed.

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CA 83:162163w, Tseng et al., 1975.
CA 102:147653y, Yamamoto et al., 1984.

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