Drug – bio-affecting and body treating compositions – Designated organic active ingredient containing – Having -c- – wherein x is chalcogen – bonded directly to...
Patent
1988-03-03
1990-05-08
Robinson, Douglas W.
Drug, bio-affecting and body treating compositions
Designated organic active ingredient containing
Having -c-, wherein x is chalcogen, bonded directly to...
514913, A61K 3144
Patent
active
049238779
ABSTRACT:
An antiglaucoma composition containing as the active component a s-/-/-2,3 dihydroxy-9,10,11-trimethoxy-5,8,13,13a-tetrahydro-6H-dibenzo (a,f) quinolizine hydrochloride of the general formula: ##STR1## where R.sub.1 .dbd.R.sub.2 .dbd.R.sub.3 .dbd.R.sub.4 .dbd.H.dbd.R.sub.5 .dbd.R.sub.6 .dbd.R.sub.7 .dbd.CH.sub.3 O
The composition is used as an ophthalmic solution in a method for treating glaucoma by administering a therapeutic dose of 2 to 3 drops two to four times daily to a host such as a warm-blooded animal having glaucoma.
REFERENCES:
Goodman and Gilman's, Seventh Edition, pp. 123-125, (1985).
Berezhinskaya E. E. Aleshinskaya--Pharmacol i toxicol.
Ivanov C. N. Ivanova et al., Inventor's Cert. No. 32353.
Amin A. T. Subbajah--Canada J. Microbio., 15(9), 1969.
Arrata M.--Ocular phar. London Acad., 1980.
Ikram L.--Planta Med., 28(4), 1975, pp. 353-358.
Jamahara J. T. Konoshima--Chem. Pharm. Bull., 1976.
Katz, I.--Invest. Ophthalmol. Vis. Sci., 15, 1976.
Katz, I.--Ann. Phthalmol., 10m, 1978, pp. 847-850.
Kosman, M.--JAMA, 241, 1979, p. 2301-2303.
Leydhecker, W.--Klin. Monatsblaelter fuer Augenheilkunde, 171, 1977.
Schiffer, H.--Merck Sharp Dohme Intern., 1978, pp. 49-52.
Zimmermann, T.--Ophthalmol. Vis. Sci., 16, 1977, pp. 687-688.
Berova Nikolina D.
Gentcheva Dobrinka G.
Ivanov Chavdar B.
Jelyazkov Deltcho G.
Marinova Viola M.
Fay Zohreh A.
Pharmachim
Robinson Douglas W.
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