Complex containing coagulation factor IX

Details Complex containing coagulation factor IX Complex containing coagulation factor IX

1992-01-21

1994-01-25

Nutter, Nathan M.

Synthetic resins or natural rubbers -- part of the class 520 ser

Synthetic resins

Mixing of two or more solid polymers; mixing of solid...

530381, 210656, C08G 6348, C08G 6391, A61K 3514

Patent

active

052816613

ABSTRACT:
Factor IX is selectively adsorbed by means of hydrophobic chromatography from an aqueous mixture containing at least one plasma zymogen or a vitamin-K dependent protein in addition to factor IX. By this method, the efficient enrichment of factor IX for the production of pharmaceutical preparations has become possible.

REFERENCES:
patent: 4820805 (1989-04-01), Neurath et al.
patent: 4822872 (1989-04-01), Kameyama et al.
patent: 5061789 (1991-10-01), Moller et al.
Vukovich et al., "Separation of Human Blood Clotting Factors from Fibrinogen and other Plasma Proteins by Chromatography on Butyl-Sepharose", Folia Haematol. 107:1, 148-151 (1979).
Scopes, "Separation by Adsorption", Protein Purification Principles and Practice, 176-179 (1987).
A copy of the European search Report.
Einarsson et al., "Removal of Hepatitis B Virus From A Concentrate Of Coagulation Factors II, VII, IX and X By Hydrophobic Interaction Chromatography", J. Vir. Met., 3:213-228 (1981).
Miletich et al., "The Synthesis of Sulfated Dextran Beads for Isolation of Human Plasma Coagulation Factors II, IX, and X", Anal. Biochem., 105:304-310 (1980).
H. G. J. Brummelhuis, "Preparation of the Prothrombin Complex", Methods of Plasma Protein Fractionation, ed. J. M. Curling, pp. 117-128, Acad. Press (1980).

Affiliated with

Also associated with

Rating

Complex containing coagulation factor IX does not yet have a rating. At this time, there are no reviews or comments for this patent.

If you have personal experience with Complex containing coagulation factor IX, we encourage you to share that experience with our LandOfFree.com community. Your opinion is very important and Complex containing coagulation factor IX will most certainly appreciate the feedback.

Rate now

Comments { 0 }

Profile ID: LFUS-PAI-O-728352