Drug – bio-affecting and body treating compositions – Immunoglobulin – antiserum – antibody – or antibody fragment,... – Monoclonal antibody or fragment thereof
Reexamination Certificate
2011-03-22
2011-03-22
Kolker, Daniel E (Department: 1649)
Drug, bio-affecting and body treating compositions
Immunoglobulin, antiserum, antibody, or antibody fragment,...
Monoclonal antibody or fragment thereof
C514S408000, C514S422000, C514S423000, C530S388250, C530S387100, C530S387900, C548S400000, C548S524000, C548S565000
Reexamination Certificate
active
07910106
ABSTRACT:
The invention describes the use of an antibody specific for serum amyloid P component, for the treatment or prophylaxis of amyloidosis, and the use of a compound which depletes serum amyloid P component from the circulation in combination with an antibody specific for serum amyloid P component.
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Kuby J. Immunology, Third Edition, 1997, W.H. Freeman & Co., New York, pp. 131-134.
Alberts B et al. Molecular Biology of the Cell, 3rd Edition, 1994, pp. 1216-1220.
Hazenberg BP et al. Diagnostic performance of 123I-labeled serum amyloid P component scintigraphy in patients with amyloidosis. Am J Med. Apr. 2006; 119(4):355.e15-24.
Santa Cruz Biotechnology, Inc. Research Antibodies Catalog '07, entry for SAP (SAP-5) sc-59686, p. 576, Jan 2007.
Zandman-Goddard G et al. Anti-serum amyloid component P antibodies in patients with systemic lupus erythematosus correlate with disease activity. Ann Rheum Dis. 2005; 64:1698-1702.
Pepys et al., Targeted pharmacological depletion of serum amyloid P component for treatment of human amyloidosis. Nature. May 16, 2002;417(6886):254-9.
Ballard Kimberly A.
Kolker Daniel E
Kowalski Thomas J.
Lu Deborah L.
Pentraxin Therapeutics Ltd.
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