Combinations of enzyme inhibitors and the use thereof

Details Combinations of enzyme inhibitors and the use thereof Combinations of enzyme inhibitors and the use thereof

2007-06-12

2007-06-12

Russel, Jeffrey Edwin (Department: 1654)

Drug, bio-affecting and body treating compositions

Designated organic active ingredient containing

Peptide containing doai

C514S019300, C514S114000, C514S119000, C514S317000, C514S326000, C514S330000, C514S365000, C514S400000, C514S422000, C514S423000, C514S576000, C514S578000, C514S579000, C514S665000

Reexamination Certificate

active

10250476

ABSTRACT:
Combination of inhibitors of dipeptidyl peptidase IV (DP IV) and enzymes having the same substrate specificity (DP IV-analogous enzymatic activity) and inhibitors of alanyl aminopeptidase (aminopeptidase N, APN) and of enzymes having the same substrate specificity (APN-analogous enzymatic activity) for a more than additive to superadditive inhibition for the treatment of arteriosclerosis, for the treatment of allergic reactions of the type I according to the Gell and Coombs classification and for the treatment of dermatological diseases with follicular and epidermal hyperkeratoses and an enhanced proliferation of keratinocytes.

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