Organic compounds -- part of the class 532-570 series – Organic compounds – Amino nitrogen containing
Patent
1998-04-07
1999-10-26
Jones, Dwayne C.
Organic compounds -- part of the class 532-570 series
Organic compounds
Amino nitrogen containing
514630, C07C23300, A01N 3718
Patent
active
059732040
ABSTRACT:
The present invention relates to 3-demethyl-thiocolchicine derivatives of general formula (I) ##STR1## in which R can be ##STR2## to a process for the preparation thereof, to pharmaceutical compositions containing them and to the use thereof for the preparation of medicaments with muscle relaxant and antiinflammatory activities.
REFERENCES:
patent: 2820029 (1958-01-01), Muller et al.
Grant & Hackh's Chemical Dictionary, 5th Edition, col. 1, p. 113, Feb. 24, 1988.
Kerekes et al., "Synthesis and Biological Effects of Novel Thiocochicines"; J. Med. Chem., vol. 28, No. 9, 1985, pp. 1204-1208, XP002069840.
Indena S.p.A.
Jones Dwayne C.
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