Organic compounds -- part of the class 532-570 series – Organic compounds – Carbohydrates or derivatives
Reexamination Certificate
2007-02-06
2007-02-06
Sullivan, Daniel M. (Department: 1636)
Organic compounds -- part of the class 532-570 series
Organic compounds
Carbohydrates or derivatives
C536S023200, C435S320100, C435S325000, C435S070100
Reexamination Certificate
active
10297563
ABSTRACT:
The present invention relates to codon optimised polynucleotides which are efficiently expressed in mammalian cells and encode insect proteins fromDermaphagoidsdust mite. In particular, the optimised codon polynucleotides encode a protein fromDermaphagoides pteronyssinus,such as DerP1 or proDerP1. The present invention also provides methods of preparing pharmaceutical compositions comprising the expression of the codon optimised polynucleotides, and vectors and transformed host cells comprising them.
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Bollen Alex
Jacobs Paul
Jacquet Alain
Massaer Marc Georges Francis
Fedon Jason C.
Gimmi Edward R.
GlaxoSmithKline Biologicals S.A.
Kinzig Charles M.
McGillem Laura
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