Coated implantable medical device

Details Coated implantable medical device Coated implantable medical device

2011-01-04

2011-01-04

Prebilic, Paul (Department: 3774)

Prosthesis (i.e., artificial body members), parts thereof, or ai

Arterial prosthesis

Stent in combination with graft

C623S001420, C623S001430

Reexamination Certificate

active

07862605

ABSTRACT:
A coated implantable medical device10includes a structure12adapted for introduction into the vascular system, esophagus, trachea, colon, biliary tract, or urinary tract, and at least one layer18of a bioactive agent posited over at least one surface of the structure12. Optionally, the device10can include at least one porous, preferably polymeric layer20posited over the layer18of bioactive agent, and can alternatively or additionally include at least one coating layer16posited on one surface of the structure12, the at least one layer18of bioactive agent being posited in turn on at least a portion of the coating layer16. The porous layer20and the coating layer16each provide for the controlled release of the bioactive material from the device10. The structure12is preferably configured as a stent graft. The polymer of the porous layer20is preferably applied by vapor or plasma deposition. It is particularly preferred that the polymer is a polyamide, parylene or a parylene derivative which is deposited without solvents, heat or catalysts, but rather by condensation of a monomer vapor.

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