Drug – bio-affecting and body treating compositions – Designated organic active ingredient containing – Having -c- – wherein x is chalcogen – bonded directly to...
Reexamination Certificate
2007-05-15
2009-12-01
Wilson, James O (Department: 1624)
Drug, bio-affecting and body treating compositions
Designated organic active ingredient containing
Having -c-, wherein x is chalcogen, bonded directly to...
C544S244000
Reexamination Certificate
active
07625910
ABSTRACT:
The present invention relates to a novel co-crystal of 2-{ethyl[3-({4-[(5-{2-[(3-fluorophenyl)amino]-2-oxoethyl}-1H-pyrazol-3-yl)amino]quinazolin-7-yl}oxy)propyl]amino}ethyl dihydrogen phosphate (AZD1152) which is an aurora kinase inhibitor that is useful in the treatment of hyperproliferative diseases such as cancer.
REFERENCES:
patent: 2006/0116357 (2006-06-01), Heron et al.
patent: 2004/058781 (2004-07-01), None
Berge et al. Pharmaceutical Salts, 1977, Journal of Pharmaceutical Sciences, 66, 1-19.
Sependa George Joseph
Storey Richard
AstraZeneca AB
McDowell Brian
Wilson James O
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