Cloning and exprssion of humanized monoclonal antibodies against

Chemistry: molecular biology and microbiology – Micro-organism – tissue cell culture or enzyme using process... – Recombinant dna technique included in method of making a...

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435 7021, 4351722, 4352523, 4353201, 435325, 536 2353, C12P 2104, C12N 1500, C12N 120, C07H 2104

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057704031

ABSTRACT:
Monoclonal antibodies are provided which are specific for human interleukin-4. Also provided are complementary DNAs which encode the heavy and light chain variable regions of such monoclonal antibodies and complementarity determining regions from such DNAs; and kits and methods for detecting, measuring and immunopurifying human interleukin-4, and for blocking the biological activity of human interleukin-4.

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