Chemistry: molecular biology and microbiology – Micro-organism – tissue cell culture or enzyme using process... – Recombinant dna technique included in method of making a...
Patent
1995-06-06
1998-06-23
Caputa, Anthony C.
Chemistry: molecular biology and microbiology
Micro-organism, tissue cell culture or enzyme using process...
Recombinant dna technique included in method of making a...
435 7021, 4351722, 4352523, 4353201, 435325, 536 2353, C12P 2104, C12N 1500, C12N 120, C07H 2104
Patent
active
057704031
ABSTRACT:
Monoclonal antibodies are provided which are specific for human interleukin-4. Also provided are complementary DNAs which encode the heavy and light chain variable regions of such monoclonal antibodies and complementarity determining regions from such DNAs; and kits and methods for detecting, measuring and immunopurifying human interleukin-4, and for blocking the biological activity of human interleukin-4.
REFERENCES:
patent: 5041381 (1991-08-01), Abrams et al.
patent: 5585089 (1996-12-01), Queen et al.
Bird et al., 1988, Science 242:423-426.
Bird and Walker, 1991, TIBTECH 9:132-137.
Casali et al., Science 234:476 (1986).
Jameson et al., Nature 341:465 (1989).
Kabat et al., Sequences of Proteins of Immunological Interest, 4th Edition, U.S. Dept. of Health and Human Services, National Institutes of Health (1987). pp. vii-xliv.
Lewis et al., Gene 101297 (1991).
Queen et al., Proc. Natl. Acad. Sci. USA 86:10029 (1989).
Riechmann et al., Nature 332:323 (1988).
Saiki et al., Science 239:487 (1988).
Burgess et al (J. of Cell Biology vol. 111 Nov. 1990 pp. 2129-2138).
Lazar et al (Molecular & Cellular Biology Mar. 1988 pp. 1247-1252).
Morrison et al Advances in Immunology vol. 44 pp. 65-92, 1989.
Roberts et al Nature vol. 328 pp. 731-735 Aug. 1987.
Dalie Barbara
Le Hung V.
Miller Kenneth
Murgolo Nicholas J.
Nguyen Hanh
Caputa Anthony C.
Dulak Norman C.
Foulke Cynthia L.
Navarro Mark
Schering Corporation
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