Clonidine assay

Details Clonidine assay Clonidine assay

1977-05-10

1978-06-13

Padgett, Benjamin R.

Drug, bio-affecting and body treating compositions

Radionuclide or intended radionuclide containing; adjuvant...

Molecular bilayer structure

23230B, 260112R, 424 12, 424251, 544264, G01N 3316, A61K 4300, C07G 700, A61K 3900

Patent

active

040949648

ABSTRACT:
A sensitive immunoassay for clonidine, 2-(2,6-dichloroanilino)-2-imidazoline hydrochloride is described. To prepare the clonidine selective antiserum, an antigen is made comprising 4-[[6-[2,4-dichloro-3(4,5-dihydro-1H-imidazol-2-yl)amino]hydroxyphenyl]azo ]benzoic acid covalently bonded to an immunogenic carrier material through a peptide bond formed from said carboxyl group and amino groups contained in said immunogenic carrier material and the antigen is injected into a suitable host animal to elicit the desired antiserum.

REFERENCES:
frydman, Chemical Abstracts, vol. 84, No. 9, Mar. 1, 1976, p. 5, Abstract No. 53715c.
Rouot et al., Chemical Abstracts, vol. 85, No. 9, Aug. 30, 1976, p. 17, Abstract No. 56532x.

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