Chromone derivative, and aldose reductase inhibitor comprising s

Details Chromone derivative, and aldose reductase inhibitor comprising s Chromone derivative, and aldose reductase inhibitor comprising s

1995-06-06

1997-10-07

Chan, Nicky

Organic compounds -- part of the class 532-570 series

Organic compounds

Heterocyclic carbon compounds containing a hetero ring...

549401, 5483051, 548186, 548159, 548136, 548135, 5462831, 544362, 544364, 544376, C07D31154, C07D40502, C07D40712

Patent

active

056750234

ABSTRACT:
The present invention relates to a chromone derivative and an aldose reductase inhibitor comprising said compound as efective component, which is represented by the following formula: ##STR1## wherein R.sub.1 and R.sub.2 each represent a lower alkyl group, etc., R.sub.3 represents an oxygen atom, a sulfur atom, etc., R.sub.7 represents a phenyl group substituted or not substituted, etc., and R represents a hydrogen atom or a lower alkoxy group. The present compounds exhibit superior inhititory action on aldose reductase and are useful for the treatment of various complications of diseases in diabetes, such as cataract, retinopathy, keratopathy, nephropathy, and neuropathy.

REFERENCES:
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