Chorionic gonadotropin derived antigen for early pregnancy test

Chemistry of carbon compounds – Miscellaneous organic carbon compounds – C-metal

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260112B, 260121, 2601125LH, 424 85, 424 88, A61K 3550, A61K 39385, A61K 39395, A61K 3944

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active

042684358

ABSTRACT:
Antisera suitable for detecting the presence of human chorionic gonadotropin in body fluids by immunoassay are prepared by administering to a host animal an antigen comprising the .beta.-subunit of human chorionic gonadotropin which has been modified by cleaving and optionally conjugating the thus modified .beta.-subunit with a protein or hapten capable of enhancing the immunogenetic potency of the antigen. The antigens are also useful for the contraceptive purposes to terminate pregnancy.

REFERENCES:
patent: 3903262 (1975-09-01), Pappenhagen et al.
patent: 3992514 (1976-11-01), Donini
patent: 4016250 (1977-05-01), Saxena
patent: 4161519 (1979-07-01), Talwar
Biochem. Biophys. Res. Comm., vol. 70, No. 2, May 17, 1976, pp. 525-532, Bahl et al.
Talwar et al., Proc. Nat. Acad. Sci., U.S.A., vol. 72, No. 1, Jan. 1976, pp. 218-222.
Bahl et al., Chem. Abst., vol. 85, Sep. 1976, 73750j.

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