Drug – bio-affecting and body treating compositions – Designated organic active ingredient containing – Peptide containing doai
Patent
1993-04-01
1997-01-14
Weimar, Elizabeth C.
Drug, bio-affecting and body treating compositions
Designated organic active ingredient containing
Peptide containing doai
514 19, 546143, 546146, 546147, 548495, 548496, 530331, C07D20918, C07D21700, C07D20920, A61K 3800
Patent
active
055939678
ABSTRACT:
Novel cholecystokinin antagonists useful as agents in the treatment of obesity, hypersecretion of gastric acid in the gut, gastrin-dependent tumors, or as antipsychotics are disclosed. Further, the compounds are antianxiety agents and antiulcer agents. They are agents useful for preventing the response to the withdrawal from chronic treatment with use of nicotine, diazepam, alcohol, cocaine, coffee, or opioids. The compounds of the invention are also useful in treating and/or preventing panic. Also disclosed are pharmaceutical compositions and methods of treatment using the antagonists as well as processes for preparing them and novel intermediates useful in their preparation. An additional feature of the invention is the use of the subject compounds in diagnostic compositions.
REFERENCES:
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Holmes Ann
Horwell David C.
Kleinschroth Jurgen
Padia Janak K.
Rees David C.
Anderson Elizabeth M.
Marshall Sg
Warner-Lambert & Company
Weimar Elizabeth C.
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