Organic compounds -- part of the class 532-570 series – Organic compounds – Carboxylic acid esters
Reexamination Certificate
2005-04-08
2010-06-15
Puttlitz, Karl J (Department: 1621)
Organic compounds -- part of the class 532-570 series
Organic compounds
Carboxylic acid esters
C560S132000, C564S336000, C564S337000, C514S476000
Reexamination Certificate
active
07737295
ABSTRACT:
Compounds of Formula I, including pharmaceutically acceptable salts of the compounds, are CETP inhibitors, and are useful for raising HDL-cholesterol, reducing LDL-cholesterol, and for treating or preventing atherosclerosis. In the compounds of Formula 1, A1and A2 are each an aromatic ring, a 5-6-membered heterocyclic ring, an aromatic ring fused to a heterocyclic ring, a phenyl ring fused to a heterocyclic ring, or a cycloalkyl ring.
REFERENCES:
patent: 2002/0035136 (2002-03-01), Liu et al.
patent: 2005/0059810 (2005-03-01), Maeda et al.
patent: WO03/064376 (2003-08-01), None
patent: WO2004/020393 (2004-03-01), None
patent: WO2004/092136 (2004-10-01), None
Lin N-H et al. “Siynthesis and biological evaluation of 1-benzyl-5-(3-biphenyl-2-yl-propyl)-1H-imidazole as novel farnesyltransferase inhibitor”; Bioorganic & Medicinal Chemistry Letters, Pergamon, Elsevier Science, GB; vol. 14, No. 20, Oct. 18, 2004 pp. 5057-5062 XP004565431; Compounds 20, 21.
Ali Amjad
Bohn Joann
Deng Qiaolin
Lu Zhijian
Quraishi Nazia
Daniel Mark R.
McGinnis James L.
Merck Sharp & Dohme Corp.
Puttlitz Karl J
LandOfFree
CETP inhibitors does not yet have a rating. At this time, there are no reviews or comments for this patent.
If you have personal experience with CETP inhibitors, we encourage you to share that experience with our LandOfFree.com community. Your opinion is very important and CETP inhibitors will most certainly appreciate the feedback.
Profile ID: LFUS-PAI-O-4229880