Certain substituted amides, method of making, and method of...

Details Certain substituted amides, method of making, and method of... Certain substituted amides, method of making, and method of...

2011-05-24

2011-05-24

Balasubramanian, Venkataraman (Department: 1624)

Organic compounds -- part of the class 532-570 series

Organic compounds

Nitrogen attached directly or indirectly to the purine ring...

C514S252100

Reexamination Certificate

active

07947835

ABSTRACT:
At least one chemical entity chosen from compounds of Formula 2and pharmaceutically acceptable salts, solvates, chelates, non-covalent complexes, prodrugs, and mixtures thereof is described herein.Pharmaceutical compositions comprising at least one chemical entity of the invention, together with at least one pharmaceutically acceptable vehicle chosen from carriers adjuvants, and excipients, are described.Methods of treating patients suffering from certain diseases responsive to inhibition of Btk activity and/or B-cell activity are described. Methods for determining the presence of Btk in a sample are described.

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