Organic compounds -- part of the class 532-570 series – Organic compounds – Heterocyclic carbon compounds containing a hetero ring...
Patent
1988-07-05
1990-10-16
Rotman, Alan L.
Organic compounds -- part of the class 532-570 series
Organic compounds
Heterocyclic carbon compounds containing a hetero ring...
546262, 546271, 548411, 548450, 548484, C07D40112, A61K 3144
Patent
active
049636863
ABSTRACT:
The new pyrrolobenzimidazoles according to the present invention are compounds of the general formula: ##STR1## wherein R.sub.1 is a hydrogen atom or an alkyl, alkenyl or cycloalkyl radical, R.sub.2 is a hydrogen atom, an alkyl or alkenyl radical or a cyano group or a carbonyl group substituted by a hydroxyl or hydrazino group or by an alkyl, alkoxy, amino, alkylamino or dialkylamino group or together with R.sub.1 represents a cycloalkylene radical or R.sub.1 and R.sub.2 together form an alkylidene or cycloalkylidene radical, X is a valency bond, a C.sub.1 -C.sub.4 alkylene radical or a vinylene radical, T is an oxygen or sulphur atom and Py is a 2-, 3- or 4-pyridyl radical which optionally carries an oxygen atom on the ring heteroatom and/or can be substituted one or more times by alkyl, alkoxy, hydroxyl, cyano or nitro, as well as by halogen; the tautomers thereof and the physiologically acceptable salts thereof with inorganic and organic acids.
REFERENCES:
patent: 4696931 (1987-06-01), Hauel et al.
"Uber Derivate des m- und P-Phenylen-diamins sowie des 6-Amino-Oxindols," Paul Ruggle and Richard Grand, Helv. Chem. Acta. 20, 373-386 (1973).
Holck Jens-Peter
Kampe Wolfgang
Mertens Alfred
Muller-Beckmann Bernd
Sponer Gisbert
Boehringer Mannheim GmbH
Rotman Alan L.
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