Certain anti-tumor duocarmycin antibiotics from streptomyces

Details Certain anti-tumor duocarmycin antibiotics from streptomyces Certain anti-tumor duocarmycin antibiotics from streptomyces

1989-04-28

1991-02-19

Rotman, Alan L.

Organic compounds -- part of the class 532-570 series

Organic compounds

Heterocyclic carbon compounds containing a hetero ring...

546 84, 514411, 514292, C07D48704, C07D51900, A61K 3140, A61K 3141

Patent

active

049945785

ABSTRACT:
Novel substances exhibiting antimicrobial activity and antitumor activity, a process for producing them by cultivating a microorganism belonging to the genus Streptomyces and capable of producing them and derivatives of such substances.

REFERENCES:
Ichimura et al, Journal of Antibiotics, 49:1285-1288 (1988).
Takahashi et al, Journal of Antibiotics, 41:1915-1917 (1988).
Ogawa et al, Journal of Antibiotics, 42:1299-1301 (1989).
Ohba et al, Journal of Antibiotics, 41:1515-1519 (1988).
Kelly et al, Journal American Chemical Society, 109:6837-6838 (1987).
30th Symposium-The Chemistry of Natural Products, Fukuoka 1988, pp. 300-307.

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