Cephem compounds and process for preparing the same

Details Cephem compounds and process for preparing the same Cephem compounds and process for preparing the same

1982-04-09

1985-12-24

Rizzo, Nicholas S.

Organic compounds -- part of the class 532-570 series

Organic compounds

Chalcogen in the nitrogen containing substituent

544 26, 544 27, C07D50157, A61K 31545

Patent

active

045607508

ABSTRACT:
Disclosed is a novel cephem compound represented by the formula: ##STR1## wherein R.sup.1, R.sup.2, R.sup.3, R.sup.4 and Y are as defined in the specification, which is a useful intermediate for synthesizing various cephalosporin antibiotics having a methoxy group at the 7.alpha.-position thereof. Also disclosed is a process for preparing the same.

REFERENCES:
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patent: 4260746 (1981-04-01), Taylor et al.
patent: 4317907 (1982-03-01), Saikama et al.
Atsumi et al., Tetrahedron Letters, vol. 23, No. 29, pp. 2977-2980 (1982).
Communications to the Editor, pp. 2401-2403; Baldwin et al.
J. Org. Chem., vol. 38, No. 5, 1973, pp. 943-950; Slusarchyk et al.
Tetrahedron Letters No. 31, pp. 2705-2708, 1975, Pergamon Press; Yanagisawa et al.
Tetrahedron Letters No. 16, pp. 1307-1310, 1976, Pergamon Press; Sugimura et al.
Communications to the Editor, pp. 5505-5507; Kobayashi et al.
Journal of the American Chemical Society/94:4/2/23/72; pp. 1408-1410; Cama et al.

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