Organic compounds -- part of the class 532-570 series – Organic compounds – Chalcogen in the nitrogen containing substituent
Patent
1975-06-19
1978-09-12
Daus, Donald G.
Organic compounds -- part of the class 532-570 series
Organic compounds
Chalcogen in the nitrogen containing substituent
544 26, 424246, 260308C, 260308R, C07D50154, C07D50156, A61K 31545
Patent
active
041139445
ABSTRACT:
A cephalosporin compound represented by the formula (I) or (I') ##STR1## wherein R.sup.1 represents a phenyl group, a 2-thienyl group or a phenoxy group; R.sup.2 represents a hydrogen atom, an alkyl group having 1 to 4 carbon atoms which may be substituted with a phenyl group, an alkoxy group having 1 to 4 carbon atoms or a halogen atom, or a phenyl group which may be substituted with one or two groups selected from the group consisting of a halogen atom, a nitro group, an alkyl group having 1 to 4 carbon atoms and an alkoxy group having 1 to 4 carbon atoms; R.sup.3 represents a hydrogen atom or an alkyl group having 1 to 4 carbon atoms which may be substituted with a monoalkylamino group having 1 to 4 carbon atoms in the alkyl moiety thereof, a dialkylamino group having 1 to 4 carbon atoms in each alkyl moiety thereof, a halogen atom or a phenyl group which may be substituted with one to three groups selected from the group consisting of a halogen atom, a nitro group, an alkyl group having 1 to 4 carbon atoms and an alkoxy group having 1 to 4 carbon atoms; R.sup.4 represents an alkyl group having 1 to 4 carbon atoms; A has up to 15 carbon atoms and represents a straight or branched chain alkylene group, a straight or branched chain alkenylene group, a straight or branched chain alkadienylene group or a phenylene group, and n is 0 or 1; or the salt thereof; and a process for preparing the same.
REFERENCES:
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patent: 3641021 (1972-02-01), Ryan
patent: 3819623 (1974-06-01), Takano et al.
patent: 3985739 (1976-10-01), Dunn et al.
patent: 3989694 (1976-11-01), Berges
Noller, Chemistry of Organic Compounds, W. B. Saunders & Co., Philadelphia (1965), pp. 597, 674, 676, 695.
Fuson, Reactions of Organic Compounds, Wiley & Sons, Inc., N.Y. (1964), pp. 664-669.
Kai Fumio
Kawasaki Toyoaki
Saito Toshinori
Seki Shigeo
Daus Donald G.
Meiji Seika Kaisha Ltd.
Rivers Diana G.
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