Cephalosporin derivative

Details Cephalosporin derivative Cephalosporin derivative

1995-02-07

1997-03-04

Ford, John M.

Drug, bio-affecting and body treating compositions

Designated organic active ingredient containing

Heterocyclic carbon compounds containing a hetero ring...

540225, 540227, 514203, 514205, C07D50136, A61K 31545

Patent

active

056079273

ABSTRACT:
An aminothiazolyl- or aminothiadiazolyl-cephalosporin derivative represented by the following general formula (I) which has a condensed-ring thio group as a 3-positioned substituent group that contains a thiazolylthio group, an oxazolylthio group or a heterocyclic ring thereof as one of the ring components. The compound according to the present invention has excellent activities to inhibit growth of various bacteria, especially Gram-positive bacteria including methicillin-resistant Staphylococcus aureus (MRSA), and therefore, the antibacterial agent comprising, as an active ingredient, the inventive compound can be used as a therapeutic drug for the treatment of various bacterial infections. ##STR1##

REFERENCES:
patent: 3992377 (1976-11-01), Chauvette et al.
patent: 4256739 (1981-03-01), Woodward et al.
patent: 5247073 (1993-09-01), Ternanhy et al.

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