Drug – bio-affecting and body treating compositions – Designated organic active ingredient containing – Heterocyclic carbon compounds containing a hetero ring...
Patent
1987-04-07
1989-06-13
Warden, Robert J.
Drug, bio-affecting and body treating compositions
Designated organic active ingredient containing
Heterocyclic carbon compounds containing a hetero ring...
514206, 540222, 540227, A61K 31545, C07D50124
Patent
active
048393509
ABSTRACT:
A class of new caphalosporin compounds (syn-isomer) is now provided, which is useful as antibacterial agent and is represented by the general formula (I) ##STR1## wherein R.sup.1 is an amino group or a protected amino group; R.sup.2 is a lower alkyl group, a carboxymethyl group or a protected carboxymethyl group; R.sup.3 is a hydrogen atom, a salt-forming cation or a carboxyl-protecting group; A is an unsubstituted or substituted phenyl group, an unsubstituted or substituted furyl group, an unsubstituted or substituted thiazolyl group or an unsubstituted or substituted 3-lower-alkylthiazolio group, and a pharmaceutically acceptable salt or ester thereof.
REFERENCES:
patent: 4255423 (1981-03-01), Beattie
patent: 4307116 (1981-12-01), Farge
patent: 4482551 (1984-11-01), Furlenmeier
Dunn, J. Antimicrobial Chemotherapy (1982), 10, Supplement C, pp. 1-10.
Atsumi Kunio
Fukatsu Shunzo
Kondo Shin-ichi
Nishihata Ken
Sakagami Kenji
Benson Robert
Meiji Seika Kaisha Ltd.
Susumu Mitsuhashi
Warden Robert J.
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