Cleaning compositions for solid surfaces – auxiliary compositions – Cleaning compositions or processes of preparing – For cleaning a specific substrate or removing a specific...
Patent
1998-04-08
2000-09-05
Wax, Robert A.
Cleaning compositions for solid surfaces, auxiliary compositions
Cleaning compositions or processes of preparing
For cleaning a specific substrate or removing a specific...
435209, C11D 300, C12N 942
Patent
active
061142964
ABSTRACT:
The present invention provides variants of a parent cellulase, such as, e.g., a cellulase classified in family 45 such as a Humicola insolens 43 kD endoglucanase, comprising a cellulose binding domain (CBD), a catalytically active domain (CAD), and a region linking the CBD and CAD (the linking region), wherein one or more amino acid residues of the CBD, CAD, or linking region is deleted or substituted by one or more amino acid residues and/or one or more amino acids are added to the linking region and/or another CBD is added at the opposite end of the CAD. Such variants have improved properties as regards, e.g., alkaline activity, compatibility with detergent composition ingredients, particular soil removal, color clarification, defuzzing, depilling, harshness reduction, and sensitivity to anionic surfactants. Such variants are useful, e.g., in detergent compositions, for textile treatment, in paper pulp processing, for animal feed, and for stone-washing of jeans.
REFERENCES:
H.J. Gilbert et al., "The N-Terminal Region of an Endoglucanase From Pseudomonas FluorescensSubspecies CellulosaConstitutes A Cellulose-Binding Domain That is Distinct From the Catalytic Centre", Molecular Microbiology (1990) 4(5), pp. 759-767.
A. Belaich et al., "The Catalytic Domain of Endoglucanase A From Clostridium Cellulolyticum: Effects of Arginine 79 and Histidine 122 Mutations on Catalysis", Journal of Bacteriology, Jul. 1992, pp. 4677-4682 .
Fredholm Henrik
Hjorth Carsten Mailand
Nielsen Egon
Rasmussen Grethe
Rosholm Peter
Esq. Reza Green
Novo Nordisk A S
Wax Robert A.
Zelson Esq. Steve T.
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