Organic compounds -- part of the class 532-570 series – Organic compounds – Carbohydrates or derivatives
Reexamination Certificate
2008-07-29
2008-07-29
Campell, Bruce (Department: 1648)
Organic compounds -- part of the class 532-570 series
Organic compounds
Carbohydrates or derivatives
C424S207100, C424S093100, C514S04400A
Reexamination Certificate
active
07405292
ABSTRACT:
This invention provides cellular gene products which have anti-apoptotic activity in HIV-1 infected cells and provides agents for the inhibition of the cellular gene products.
REFERENCES:
patent: 6228585 (2001-05-01), Dieckgraefe
patent: 6455674 (2002-09-01), Einat
patent: 6555667 (2003-04-01), Einat
patent: 2006/0240022 (2006-10-01), Klippel-Giese et al.
patent: WO 99/09049 (1999-02-01), None
patent: WO 2004/035615 (2004-04-01), None
Qiagen Product Guide 2001 pp. 40-51.
Lee et al. Nature Biotechnology 2002, vol. 19, pp. 500-505.
Samuel C Nature Biotechnology 2004, vol. 22, No. 3, pp. 280-282.
Novina et al. Nature medicine Jul. 2002, vol. 8, No. 7, pp. 681-686.
McManus et al. J. Immunol. 2002, vol. 169, pp. 5754-5760.
Kim, T.A., et al., “HIV-1 tat-mediated apoptosis in human brain microvascular endothelial cells,” J. Immunol., 170:2629-2637, (2003).
Elbim, C., et al., “Redox and activation status of monocytes from human immunodeficiency virus-infected patients: relationship with viral load,” J. Virology, 73:4561-4566, 1999.
Finzi, D. et al. “Identification of a Reservoir for HIV-1 in Patients on Highly Active Antiretroviral Therapy”; [EBSCO Host Research Databases] Science, vol. 278, 12 pgs, 1997.
Emerman, M. et al. “HIV-1 Regulatory/Accessory Genes: Keys to Unraveling Viral and Host Cel Biology”; [EBSCO Host Research Databases]Science, vol. 280:p1880, 5p.,1998.
Wong, J.K. et al. “Recovery of Replication-Competent HIV Despite Prolonged Suppression of Plasma Viremia”; [EBSCO Host Research Databases] Science, vol. 278:1297, 5p, 1997.
Corbeil, J. et al. “Temporal Gene Regulation During HIV-1 Infection of Human CD4+ T Cells”; Genome Research, 11: 1198-1204 (2001).
Diatchenko, L. et al. “Suppression subtractive hybridization: A method for generating differentially regulated or . . . ”; Proc. Natl. Acad. Sci USA, 93: 6025-6030 (1996).
Geiss, G.K. et al. “Large-Scale Monitoring of Host Cell Gene Expression during HIV-1 Infection Using cDNA Microarrays”; Virology, 266: 8-16 (2000).
Ryo, A. et al. “Serial analysis of gene expression in HIV-1 -infected T celllines”;FEBS Letters, 462: 182-186(1999).
Simm, M. et al. “Cloning of differentially expressed genes in an HIV-1 resistant T cell clone by rapid subtraction hybridization, RaSH”; Gene, 269: 93-101 (2001).
Folks, T.M. et al. “Biological and Biochemical Characterization of a Cloned LEU-3- Cell Surviving Infection with the Acquired . . . ”; J. Exp. Med. 164: 280-290 (1986).
Selliah, N. et al. “Cutting Edge: JAK3 Activation and Rescue of T Cells from HIV gp120-Induced Unresponsiveness”; The Journal of Immunology, 160: 5697-5701 (1998).
Scheuring, U.J. et al., “Differential expression profiles of apoptosis-affecting genes in HIV-infected cell lines and patient T cells”; AIDS, 13: 167-175 (1999).
Kinoshita, S. et al., “The T Cell Activation Factor NF-ATc Positively Regulates HIV-1 Replication and Gene Expression in T Cells”; Immunity, 6: 235-244 (1997).
Kinoshita, S. et al. “Host Control of HIV-1 Parasitism in T Cells by the Nuclear Factor of Activated T Cells”; Cell, 95: 595-604 (1998).
Cron, R.Q., et al. “NFAT1 Enhances HIV-1 Gene Expression in Primary Human CD4 T Cells”; Clinical Immunology, 94(3): 179-191 (2000).
Nekhai, S. et al., “Cell Cycle-Dependent Stimulation of the HIV-1 Promoter by Tat-Associated CAK Activator”; Virology, 266: 246-256 (2000).
Liu, R. et al. “Homozygous Defect in HIV-1 Coreceptor Accounts for Resistance of Some Multiply-Exposed Individuals to HIV-1 Infection”; Cell, 86: 367-377 (1996).
Bushman, F. et al. “New developments in the biology and treatment of HIV”; PNAS, 95(19): 11041-11042 (1998).
Gelezlunas, R. et al. “HIV-1 Nef inhibits ASK1-dependent death signalling providing a potential mechanism for protecting the infected host cell”; Nature, 410: 834-838 (2001).
Hoxie, J.A. et al. “Persistent Noncytopathic Infection of Normal Human T Lymphocytes with AIDS-Associated Retrovirus”; Science, New Series, 229(4720): 1400-1402 (1985).
LaCasse, R.A et al. “Fusion-Competent Vaccines: Broad Neutralization of Primary Isolates of HIV”; [EBSCO Host Research Databases] Science, 0036-8075, vol. 283:357 6p. 1999.
Perrin, L. et al. “HIV Treatment Failure: Testing for HIV Resistance in Clinical Practice”; [EBSCO Host Research Databases], Science, vol. 280, Issue 5371, p1871, 3p, 1998.
Fauci, A.S. “Host factors and the pathogenesis of HIV-induced disease”; Nature, 384(6609): 529-534 (1996).
McMichael, AJ. et al. “Escape of Human Immunodeficiency Virus from Immune Control”; Annual Review of Immunology, 15(1): 271-296 (1997).
Chun, T. et al. “Presence of an inducible HIV-1 latent reservoir during highly active antiretroviral therapy”; Proc. Natl. Acad. Sci. USA, 94: 13193-13197 (1997).
Pantaleo, G. et al. “Immunopathogenesis of HIV Infection”; Annu. Rev. Microbiol., 50:825-54 (1996).
Rowland-Jones, S. et al. “New Insights into Host Factors in HIV-1 Pathogenesis”; Cell, 104: 473-476 (2001).
Nabel, G.J. “Challenges and opportunities for development of an AIDS vaccine”; Nature, 410: 1002-1007 (2001).
Landau, N.R. “HIV Recent advances in AIDS research: genetics, molecular biology and immunology”; Current Opinion in Immunology, 11 :449-450 (1999).
Ameisen, J.C. “Apoptosis subversion: HIV-Nef provides both armor and sword”; Nature Medicine, 7(11): 1181-1182 (2001).
Casella, C.R. et al. “Vpu Increases susceptibility of Human Immunodeficiency Virus Type 1-Infected Cells to Fas Killing”; Journal of Virology, 73(1): 92-100 (1999).
Shoshani, T. et al. “Identification of a Novel Hypoxia-Inducible Factor 1-Responsive Gene, RTP801, Involved in Apoptosis”; Molecular &Cellular Biology, 22(7): 2283-2293, 2002.
Lewis, J. et al. “Disruption of Hsp90 Function Results in Degradation of the Death Domain Kinase, Receptor-interacting Protein (RIP) . . . ,” J.Biol.Chem., 275:10519-10526 (2000).
Pandey, P. et al. “Negative regulation of cytochrome c-mediated oligomerization of Apaf-1 and activation of procaspase-9 by heat shock protein 90”;EMBO J., 19:4310-4322 (2000).
Galea-Lauri, J. et al. “Increased Heat Shock Protein 90 (hsp90) Expression Leads to Increased . . . ,” The Journal of Immunology, 157: 4109-4118 (1996).
Swaroop, M. et al. “SAG/ROC2/Rbx2/Hrt2, a Component of SCF E3 Ubiquitin Ligase: Genomic Structure, a Splicing Variant . . . ”; DNA and Cell Biology, 20(7): 425-434 (2001).
Duan, H. et al. “SAG, a Novel Zinc Ring Finger Protein That Protects Cells from Apoptosis Induced b Redox Agents”; Molecular and Cellular Biol., 194: 3145-3155 1999.
Buck, et al., BioTechniques, 27(3):528-536, (1999).
Verma, et al., Nature 389:239-242, (1999).
Eck, et al., “Gene-based therapy,” in: The pharmacological basis of therapeutics, Goodman and Gilman, eds., pp. 77-101, (1996).
Orkin, et al., “Report and recommendation of the panel to assess the NIH investment in research on gene therapy,” NIH, (1995).
Change, et al., J. Biomedical Science, 7:322-333, (2000).
Parlato, et al., Cell Death and Differentiation, 7:37-47, (2000).
Yin, et al., AIDS 18:587-596, (2004).
Feit, et al., J. Pat. Trade. Off. Soc., 85:5-21 (2003).
Finkel Terri H.
Yin Jiyi
Campell Bruce
Dann Dorfman Herrell & Skillman
Li Bao Qun
Netter Robert C.
Rigaut Kathleen D.
LandOfFree
Cellular genes regulated by HIV-1 infection and methods of... does not yet have a rating. At this time, there are no reviews or comments for this patent.
If you have personal experience with Cellular genes regulated by HIV-1 infection and methods of..., we encourage you to share that experience with our LandOfFree.com community. Your opinion is very important and Cellular genes regulated by HIV-1 infection and methods of... will most certainly appreciate the feedback.
Profile ID: LFUS-PAI-O-2797473