Chemistry: molecular biology and microbiology – Measuring or testing process involving enzymes or... – Involving viable micro-organism
Reexamination Certificate
2007-01-30
2007-01-30
Lankford, Jr., Leon B. (Department: 1651)
Chemistry: molecular biology and microbiology
Measuring or testing process involving enzymes or...
Involving viable micro-organism
C435S029000, C435S004000, C435S325000, C435S326000, C435S288400, C435S305200, C435S070200, C209S017000
Reexamination Certificate
active
10206340
ABSTRACT:
The present invention provides methods and devices for screening a single cell or a small group of cells for a desired biological activity. In particular, the present invention provides for delivering cell(s) to a plurality of cell isolation regions of a cell isolation device, transferring cell(s) to a plurality of wells of a cell expansion device and then detecting the potential desired biological activity of the cell(s). Each of the receptacles comprise a recess sized to isolate a single cell or small group of cells and each of the wells encompass a cavity that provides sufficient volume for cell proliferation.
REFERENCES:
patent: 4230685 (1980-10-01), Senyei et al.
patent: 4408625 (1983-10-01), Kuhl
patent: 4508625 (1985-04-01), Graham
patent: 4582622 (1986-04-01), Ikeda et al.
patent: 4591570 (1986-05-01), Chang
patent: 4672040 (1987-06-01), Josephson
patent: 4729949 (1988-03-01), Weinreb et al.
patent: 4748124 (1988-05-01), Vogler
patent: 4777145 (1988-10-01), Luotola et al.
patent: 4910148 (1990-03-01), Sorensen et al.
patent: 4988618 (1991-01-01), Li et al.
patent: 4992377 (1991-02-01), Saxholm
patent: 5186827 (1993-02-01), Liberti et al.
patent: 5200084 (1993-04-01), Liberti et al.
patent: 5202227 (1993-04-01), Matsuda et al.
patent: 5278063 (1994-01-01), Hubbell et al.
patent: 5330911 (1994-07-01), Hubbell et al.
patent: 5395498 (1995-03-01), Gombinsky et al.
patent: 5427663 (1995-06-01), Austin et al.
patent: 5466574 (1995-11-01), Liberti et al.
patent: 5476796 (1995-12-01), Takahashi et al.
patent: 5486457 (1996-01-01), Butler et al.
patent: 5498392 (1996-03-01), Wilding et al.
patent: 5498550 (1996-03-01), Fujiwara et al.
patent: 5508164 (1996-04-01), Kausch et al.
patent: 5514340 (1996-05-01), Lansdorp et al.
patent: 5567326 (1996-10-01), Ekenberg et al.
patent: 5573942 (1996-11-01), Miyamoto
patent: 5591627 (1997-01-01), Miyamoto
patent: 5593838 (1997-01-01), Zanzucchi et al.
patent: 5602028 (1997-02-01), Minchinton
patent: 5602042 (1997-02-01), Farber
patent: 5603351 (1997-02-01), Cherukuri et al.
patent: 5612188 (1997-03-01), Shuler et al.
patent: 5646001 (1997-07-01), Terstappen et al.
patent: 5660990 (1997-08-01), Rao et al.
patent: 5665582 (1997-09-01), Kausch et al.
patent: 5681484 (1997-10-01), Zanzucchi et al.
patent: 5755942 (1998-05-01), Zanzucchi et al.
patent: 5759793 (1998-06-01), Schwartz et al.
patent: 5763203 (1998-06-01), Ugelstad et al.
patent: 5776748 (1998-07-01), Singhvi et al.
patent: 5795470 (1998-08-01), Wang et al.
patent: 5812419 (1998-09-01), Chupp et al.
patent: 5858804 (1999-01-01), Zanzucchi et al.
patent: 5876593 (1999-03-01), Liberti et al.
patent: 5912177 (1999-06-01), Turner et al.
patent: 5922284 (1999-07-01), Kinoshita et al.
patent: 5928880 (1999-07-01), Wilding et al.
patent: 5968820 (1999-10-01), Zborowski et al.
patent: 5972721 (1999-10-01), Bruno et al.
patent: 5989835 (1999-11-01), Dunlay et al.
patent: 5993665 (1999-11-01), Terstappen et al.
patent: 5993740 (1999-11-01), Niiyama et al.
patent: 5998160 (1999-12-01), Berens
patent: 5998224 (1999-12-01), Rohr et al.
patent: 6008010 (1999-12-01), Greenberger et al.
patent: 6013188 (2000-01-01), Terstappen et al.
patent: 6013532 (2000-01-01), Liberti et al.
patent: 6027945 (2000-02-01), Smith et al.
patent: 6039897 (2000-03-01), Lochhead et al.
patent: 6083761 (2000-07-01), Kedar et al.
patent: 6090251 (2000-07-01), Sundberg et al.
patent: 6110380 (2000-08-01), Barbera-Guillem
patent: 6126835 (2000-10-01), Barbera-Guillem et al.
patent: 6133043 (2000-10-01), Talley et al.
patent: 6136182 (2000-10-01), Dolan et al.
patent: 6140045 (2000-10-01), Wohlstadter et al.
patent: 6143247 (2000-11-01), Sheppard, Jr. et al.
patent: 6180239 (2001-01-01), Whitesides et al.
patent: 6180418 (2001-01-01), Lee
patent: 6184043 (2001-02-01), Fodstad et al.
patent: 6187214 (2001-02-01), Ganan-Calvo
patent: 6221663 (2001-04-01), Bhatia et al.
patent: 6235541 (2001-05-01), Brizzolara
patent: 6238538 (2001-05-01), Parce et al.
patent: 6258607 (2001-07-01), Saito et al.
patent: 6558904 (2003-05-01), Ermantraut et al.
patent: 2002/0012953 (2002-01-01), Jauho et al.
patent: 2002/0022276 (2002-02-01), Zhou et al.
patent: 0 390 634 (1995-05-01), None
patent: 63-116175 (1988-05-01), None
patent: WO 92/08133 (1992-05-01), None
patent: WO 94/11078 (1994-05-01), None
patent: WO 97/28490 (1997-08-01), None
patent: WO 99/42832 (1999-08-01), None
patent: WO 00/43783 (2000-07-01), None
patent: WO 00/54882 (2000-09-01), None
patent: WO 00/60356 (2000-10-01), None
patent: WO 01/51668 (2001-07-01), None
Yokoyama, “Production of Monoclonal Antibodies” Current Protocols in Cell Biology, 1999, 16.1.1-16.1.17.
Hornbeck et al, “Enzyme-Linked Immunosorbent Assays (ELISA)” Current Protocols in Molecular Biology, 1991, 11.2.1-11.2.22.
Castelino J., “Magnetic Activated Cell Sorting using Microfabricated Arrays”, Biomedical Physics (1999), Session Z13.001 (abstract).
Fishman D. et al., “Biological Assays in Microfabricated Structures”, SPIE (1999) 3603:192-197.
Folch A. et al., “Microengineering of Cellular Interactions”, Annu. Rev. Biomed. Eng. (2000) 2:227-256.
Love J.C. et al., “Fabrication of Three-Dimensional Microfluidic Systems by Soft Lithography”, MRS Bulletin (2001) 523-528.
Beebe et al., “Microfluidic tectonics: A comprehensive construction platform for microfluidic systems”, PNAS, 97(25):13488-13493 (2000).
Bhatia et al., “Selective Adhesion of Hepatocytes on Patterned Surfaces”, Annals New York Academy of Sciences, 745:187-209 (1994).
Blawas et al., “Protein Patterning”, Biomaterials, 19:595-609 (1998).
Boone et al., “Plastic Advances Microfluidic Devices” Analytical Chemistry, 74(3):78A-86A (2002).
Britland et al., “Micropatterning Proteins and Synthetic Peptides on Solid Supports: A Novel Application for Microelectronics Fabrication Technology”, Biotechnol. Prog.., 8:155-160 (1992).
Chen et al., “Using Self-Assembled Monolayers to Pattern ECM Proteins and Cells on Substrates”, Methods in Molecular Biology—Extracellular, Matrix Protocols, 139:209-218.
Chiu et al., “Patterned deposition of cells and proteins onto surfaces by using three-dimensional microfluidic systems”, PNAS, 97(6):2408-2413 (2000).
Dasgupta et al., “Visualizing thin-layer, 2-D flow and chemical interaction can be done simply and cheaply”, Analytical Chemistry, 74(7):209A-213A (2002).
Delamarche et al., “Patterned Delivery of Immunoglobulins to Surfaces Using Microfluidic Networks”, Science, 276:779-781 (1997).
Delamarche et al., “Microfluidic Networks for Chemical Patterning of Substrates: Design and Application to Bioassays”, J. Am. Chem. Soc., 120:500-508 (1998).
Hodneland et al., “Selective immobilization of proteins to self-assembled manolayers presenting active site-directed capture ligands”, PNAS, 99(8):5048-5052 (2002).
Jung et al.,Topographical and Physicochemical Modification of Material Surface to Enable Patterning of Living Cells, Critical Reviews in Biotechnology, 21(2):111-154 (2001).
Quake et al., “From Micro-to-Nanofabrication with Soft Materials”, Science, 290(5496):1536-1540 (2000).
Safarik et al., “Use of magnetic techniques for the isolation of cells”, Journal of Chromatography B, 722:33-53 (1999).
Saleemuddin, “Bioaffinity Based Immobilization of Enzymes”, Advances in Biochemical Engineering/Biotechnology, 64: 203-226 (1999).
Yang et al., “I1-18-stimulated GADD45β required in cytokine-induced, but not TCR-induced, IFN-γ production”,Abstracts2.1-537.42 Part 1-Experimental Biology 2001, Orlando Florida, Mar. 31-Apr. 4, 2001, FASEB Journal, Abstract 537.40.
Casagrande Rocco
Kendale Amar
Kim Enoch
Ostuni Emanuele
Schueller Olivier
Ford Allison M.
Kenyon & Kenyon LLP
Lankford , Jr. Leon B.
Surface Logix Inc.
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