Chemistry: molecular biology and microbiology – Measuring or testing process involving enzymes or... – Involving antigen-antibody binding – specific binding protein...
Reexamination Certificate
2006-10-18
2011-10-04
Gussow, Anne M. (Department: 1643)
Chemistry: molecular biology and microbiology
Measuring or testing process involving enzymes or...
Involving antigen-antibody binding, specific binding protein...
C435S006120
Reexamination Certificate
active
08030004
ABSTRACT:
Methods are disclosed for identifying agents for the treatment of cancer and/or Fanconi anemia usingXenopusegg cell free extracts from which the endogenous DNA has been removed. The assays and method described herein are easily adaptable to high throughput techniques for example to screen large numbers of agents as possible agents for the treatment of cancer and/or Fanconi anemia. Kits for carrying out the disclosed assays and methods also are disclosed. Agents identified by these methods are also disclosed as are methods for treating a subject with cancer and/or Fanconi anemia with these agents.
REFERENCES:
patent: WO 02/36761 (2002-05-01), None
patent: WO 03/039327 (2003-05-01), None
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Costanzo Vincenzo
Gautier Jean
Hoatlin Maureen
Landais Igor
Sobeck Alexandra
Gussow Anne M.
Klarquist & Sparkman, LLP
Oregon Health & Science University
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