Chemistry: molecular biology and microbiology – Micro-organism – tissue cell culture or enzyme using process... – Recombinant dna technique included in method of making a...
Patent
1991-09-20
1994-05-17
Hill, Jr., Robert J.
Chemistry: molecular biology and microbiology
Micro-organism, tissue cell culture or enzyme using process...
Recombinant dna technique included in method of making a...
435 2, 435 4, 435 6, 435 30, 435 41, 4352402, 4353201, 530350, 5303879, 530395, 53038822, 5303891, 536 231, 536 234, 536 235, C12P 2106, C12N 500, C12N 1500, C07H 1512
Patent
active
053127340
ABSTRACT:
The invention described in this disclosure relates to a cloned cDNA encoding the dopamine transporter protein usually found in certain neural cells. The invention is further directed to the purified dopamine transporter protein and its use as a biosensor material and immunogen for the production of anti-DAT1 antibodies. The disclosure also discusses methods for use of the cDNA for diagnostic and treatment applications, and methods for use of permanent cell lines transformed with the dopamine transporter cDNA for pharmaceutical screening. The use of anti-DAT1 antibodies as a diagnostic tool is also addressed.
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Kitayama Shigeo
Kuhar Michael J.
Lin Chien-Liang
Patel Amrat
Shimada Shoichi
Hill Jr. Robert J.
The United States of America as represented by the Department of
Wang Alan P.
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