cDNA cloning and expression of human liver estrogen sulfotransfe

Organic compounds -- part of the class 532-570 series – Organic compounds – Carbohydrates or derivatives

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536 231, 435193, 4353201, 4352523, 4352402, 4351723, C12N 1554, C12N 910

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active

057145946

ABSTRACT:
The present invention provides an isolated and purified human DNA molecule consisting essentially of a DNA segment encoding an estrogen sulfotransferase protein or biologically active derivative thereof.

REFERENCES:
I.A. Aksoy et al., "Cholesterol Sulfation in Human Liver: Catalysis by Dehydroepiandrosterone Sulfotransferase," Drug Metab. Dispos., 21, 268-276 (1993).
I.A. Aksoy et al., "Human liver dehydroepiandrosterone sulfotransferase: Nature and extent of individual variation", Clin. Pharmacol. Ther., 54, 498-506 (1993).
I.A. Askoy, et al., "Human Liver Estrogen Sulfotransferase: Identification by cDNA Cloning and Expression", Biochem. and Biophys. Research Commun. 200 1621-1629 (May 16, 1994).
I.A. Aksoy, et al., "Human Liver Estrogen Sulfotransferase (EST): Polymerase Chain Reaction (PCR) Cloning of cDNA", (Abstract) ISSX Proc., 4, 181, 1993.
I.A. Aksoy, et al., "Human Liver Estrogen Sulfotransferase (EST): Polymerase Chain Reaction (PCR) Cloning of cDNA", (Poster Presentation for the Fifth North American Meeting of the International Society for the Study of Xenobiotics) Oct. 18, 1993.
I.A. Aksoy, et al., "Human Estrogen Sulfotransferase. cDNA Cloning, Expression and Characterization", (Abstract), Proc. Amer. Assoc. Cancer. Res., 35, 276 (1994).
I.A. Aksoy, et al., "Human Estrogen Sulfotransferase: cDNA Cloning, Expression, and Characterization", (Poster Presentation for the Eighty-Fifth Annual Meeting of the American Association for Cancer Research (AACR)) Apr. 9-13, 1994.
I.A. Aksoy, "Pharmacogenetics of Human Liver Cytosolic Sulfotransferases: Biochemical and Molecular Studies" (May 1994).
R.J. Anderson, et al., "Phenolsulphotransferase in Human Tissue: Radiochemical Enzymatic Assay and Biochemical Properties", Clin. Chim. Acta., 103, 79-90 (1980).
R.T. Borchardt, et al., "An Ecteola-Cellulose Chromatography Assay for 3'-Phosphoadenosine 5'-Phosphosulfate: Phenol Sulfotransferase," Anal. Biochem., 130, 334-338 (1983).
M.M. Bradford, "A Rapid and Sensitive Method for the Quantitation of Microgram Quantities of Protein Utilizing the Principle of Protein-Dye Binding," Anal. Biochem., 72, 248-254 (1976).
N.R.C. Campbell et al., "Human Liver Phenol Sulfotransferase: Assay Conditions, Biochemical Properties and Partial Purification of Isozymes of the Thermostable Form," Biochem. Pharmacol., 36, 1435-1446 (1987).
W.W. Cleland, "Computer Programmes for Processing Enzyme Kinetic Data," Nature, 198, 463-465 (1963).
C.N. Falany et al., "Purification and Characterization of Human Liver Dehydroepiandrosterone Sulphotransferase," Biochem. J., 260, pp. 641-646 (1989).
A.A. Farooqui, "3'-Phosphoadenosine 5'-Phosphosulfate Metabolism in Mammalian Tissues," Int. J. Biochem., 12, pp. 529-536 (1980).
A.P. Feinberg et al., "A Technique for Radiolabeling DNA Restriction Endonuclease Fragments to High Specific Activity," Ana. Biochem., 132, 6-13 (1983).
Fiers et al., "Complete nucleodite sequence of SV40 DNA," Nature, 273, 113-120 (1978).
A. Foldes and J.L. Meek, "Rat Brain Phenolsulfotransferase-Partial Purification and Some Properties," Biochem. Biophys. Acta, 327, 365-373 (1973).
M.A. Frohman et al., "Rapid Production of Full-Length cDNAs from Rare Transcripts: Amplification Using a Single Gene-Specific Oligonucleotide Primer," Proc. Nat'l. Acad. Sci. USA, 85, 8998-9002 (1988).
F.L. Graham et al., "A New Technique for the Assay of Infectivity of Human Adenovirus 5 DNA," Virology, 52, 456-467 (1973).
F.L. Graham et al., "Characteristics of a Human Cell Line Transformed by DNA from Human Adenvirus Type 5," J. Gen. Virol., 36, 59-72 (1977).
J.S. Hernandez et al., "Sulfation of Estrone and 17.beta.-Estradiol in Human Liver: Catalysis by Thermostable Phenol Sulfotranferase and by Dehydroepiandrosterone Sulfotransferase," Drug. Metab. Dispos., 20, 413-422 (1992).
R. Hobkirk, "Steroid Sulfation: Current Concepts," Trends Endocrinol. Metab., 4, 69-74 (1993).
T. Honkasalo et al., "Determination of Phenol Sulphotransferase Activity by High-Performance Liquid Chromatography," J. Chromatogr., 424, 136-140 (1988).
Hsiao et al., "High-frequency transformation of yeast by plasmids containing the cloned yeast ARG4 gene," Proc. Natl. Acad. Sci. USA, 76, 3829-3833 (1979).
W.B. Jakoby et al., "Sulfotransferases" in Enzymatic Basis of Detoxication; vol. II, W.B. Jakoby (ed), Academic Press: New York; pp. 199-229 (1980).
G.A. Johnson et al., "Sulfation of Minoxidil by Liver Sulfotransferase," Biochem. Pharmacol., 31, 2949-2954 (1982).
R.J. Kaufman, "Identification of the Components Necessary for Adenovirus Translational Control and Their Utilization in cDNA Expression Vectors," Proc. Natl. Acad. Sci. USA, 82, 689-693 (1985).
Kingsman et al., "Replication in Saccharomyces cerevisiae of Plasmid pBR313 Carrying DNA from the Yeast trpl Region," Gene, 7, 141-152 (1979).
A-N.T. Kong et al., "Molecular Cloning of the Alcohol/Hydroxysteroid Form (mST.sub.al) of Sulfotransferase from Mouse Liver," Pharmaceut. Res. 10, 627-630 (1993).
A-N.T. Kong et al., "Molecular Cloning of cDNA Encoding the Phenol/Aryl Form of Sulfotransferase (mST.sub.pl) from Mouse Liver," Biochem. Biophys. Acta, 1171, 315-318 (1993).
J. Langridge, "Genetic and Enzymatic Experiments Relating to the Tertiary Structure of .beta.-Galactosidase," J. Bacteriol., 96, 1711-1717 (1968).
C.C. Lee et al., "Generation of cDNA Probes Directed by Amino Acid Sequence: Cloning of Urate Oxidase," Science, 239, 1288-1291 (1988).
Luckow et al., "Trends in the Development of Baculovirus Expression Vectors," Bio/Technology, 6, 47-55 (1988).
H. Luthman et al., "High Efficiency Polyoma DNA Transfection of Chloroquine Treated Cells," Nucleic Acids Res., 11, 1295-1308 (1983).
S. Maeda et al., "Production of Human .alpha.-Interferon in Silkworm using a Baculovirus Vector," Nature, 315, 592-594 (1985).
M.A. Mancini et al., "Spatio-Temporal Expression of Estrogen Sulfotransferase within the Hepatic Lobule of Male Rats: Implication of in Situ Estrogen Inactivation in Androgen Action," Endocrinology, 131, 1541-1546 (1992).
J. Mather et al., "Testicular Cell Culture," Annals N.Y. Acad. Sci., 383, 44-68 (1982).
J. Mather, "Establishment and Characterization of Two Distinct Mouse Testicular Epithelial Cell Lines," Biol. Reprod., 23, 243-252 (1980).
Alan Maxam et al., "Sequencing End-Labeled DNA with Base-Specific Chemical Cleavages," Methods in Enzymology, 65, 499-560 (1980).
J. Messing et al., "A System for Shotgun DNA Sequencing," Nucl. Acids Res., 9, 309-321 (1981).
D. Miller et al., "An Insect Baculovirus Host-Vector System for High-Level Expression of Foreign Genes," Genetic Engineering, 8, 277-298 (1986).
G.J. Mulder et al., "Sulfation," in Conjugation Reactions in Drug Metabolism; Taylor & Francis Ltd.: New York; pp. 107-161 (1990).
R.C. Mulligan et al., "Expression of a Bacterial Gene in Mammalian Cells," Science, 209, 1422-1427 (1980).
D.M. Otterness et al., "Human Liver Dehydroepiandrosterone Sulfotransferase: Molecular Cloning and Expression of cDNA," Mol. Pharmacol., 41, 865-872 (1992).
D.M. Otterness et al., "Human Liver Thermostable Phenol Sulfotransferase: Photoaffinity Labeling with 2-Iodo-4-Azidophenol," Mol. Pharmacol., 36, 856-865 (1989).
G. Pavlakis et al., "Expression of Two Human Growth Hormone Genes in Monkey Cells Infected by Simian Virus 40 Recombinants," Proc. Natl. Acad. Sci. USA, 78, 7398-7402 (1981).
R.A. Price et al., "Genetic Polymorphism for Human Platelet Thermostable Phenol Sulfotransferase (TS PST) Activity," Genetics, 122, 905-914 (1989).
A. Radiminska et al., "Human Liver Steroid Sulphotransferase Sulphates Bile Acids," Biochem. J., 272, 597-604 (1990).
G. Rein et al., "Multiple Forms of Phenolsulphotransferase in Human Tissues: Selective Inhibition by Dichloronitrophenol," Biochem. Pharmacol., 31, 1893-1897 (1982).
C. Reiter et al., "Thermolabile and Thermostable Human Platelet Phenol Sulfotransferase: Substrate Specificity and Physical Separation," Naunyn-Schmied. Archiv. Pharmacol., 324, 140-147 (1983).
J.I. Rotter et al., "A Genetic Component to the Variation of Dehydroepiandrosterone Sulfate," Metabolism, 34, 731-736 (1985).
A.K. Roy,

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