Drug – bio-affecting and body treating compositions – Conjugate or complex of monoclonal or polyclonal antibody,...
Patent
1995-06-05
2000-05-02
Chan, Christina Y.
Drug, bio-affecting and body treating compositions
Conjugate or complex of monoclonal or polyclonal antibody,...
4241301, 4241331, 4241411, 4241431, 4241531, 4241731, 4241841, 530350, 5303871, 5303873, 5303881, 5303882, 53038822, 53038873, A61K 39395, A61K 3528, C07K 1628, C07K 14435
Patent
active
06056959&
ABSTRACT:
Methods for preventing or treating an antibody-mediated diease in a patient are presented, the methods comprising administration of a monoclonal antibody capable of binding to a human CD40 antigen located on the surface of a human B cell, wherein the binding of the antibody to the CD40 antigen prevents the growth or differentiation of the B cell. Monoclonal antibodies useful in these methods, and epitopes immunoreactive with such monoclonal antibodies are also presented.
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Conroy Leah B
de Boer Mark
Blackburn Robert P.
Chan Christina Y.
Chiron Corporation
Gambel Phillip
Morley Kimberlin L.
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