Drug – bio-affecting and body treating compositions – Designated organic active ingredient containing – Having -c- – wherein x is chalcogen – bonded directly to...
Reexamination Certificate
2007-08-07
2007-08-07
McKenzie, Thomas (Department: 1625)
Drug, bio-affecting and body treating compositions
Designated organic active ingredient containing
Having -c-, wherein x is chalcogen, bonded directly to...
C514S345000, C546S301000, C546S339000
Reexamination Certificate
active
10469173
ABSTRACT:
The present invention provides a novel carboxylic acid derivative, a salt thereof or a hydrate of them which is useful as an insulin sensitizer, and a medicament comprising the derivative as the effective ingredient. More specifically, it provides a carboxylic acid compound represented by the formula (I), a salt thereof or a hydrate of them.In the formula, Ar represents a 6- to 14-membered aromatic ring group which may have at least one substituent; R1, R2, R3, R4, R5, R6, R7and R8are the same as or different from each other and each represents a hydrogen atom, a halogen atom, a hydroxyl group, a C1-6alkyl group or a C1-6alkoxy group; X represents an oxygen atom or a methylene group; Y represents a group represented by the formula (II) or (III):(wherein Z represents a group represented by the formula (IV):(wherein R9, R10, R11and R12are the same as or different from each other and each represents a hydrogen atom, a halogen atom, a hydroxyl group, a C1-6alkyl group or a C1-6alkoxy group)); m is 0 or 1; and n is 0 or 1.
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Clark Richard
Emori Eita
Harada Hitoshi
Hihara Taro
Inoue Takashi
Eisai Co. Ltd.
McKenzie Thomas
Robinson Binta
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