(Carboxyacylamino)phenylalkenamides and esters thereof as SRS-A

Details (Carboxyacylamino)phenylalkenamides and esters thereof as SRS-A (Carboxyacylamino)phenylalkenamides and esters thereof as SRS-A

1980-10-29

1981-10-20

Breitenstein, G. T.

Drug, bio-affecting and body treating compositions

Antigen, epitope, or other immunospecific immunoeffector

Recombinant or stably-transformed bacterium encoding one or...

424316, 424319, 560 37, 562442, 26050111, 2603268, 544107, 546184, A61K 3124, C07C101447, C07C101453

Patent

active

042961297

ABSTRACT:
Certain new propenamides and 2-butenamides having a (carboxyalkanamido)phenyl or a (carboxyalkenamido)phenyl group at the 3-position, and certain esters thereof, and their use for antagonizing the spasmogenic activity of slow-reacting substance of anaphylaxis (SRS-A) in a human subject. In particular, the compounds of the invention are useful for preventing and treating certain obstructive airways diseases, notably allergic bronchial asthma, allergic rhinitis and certain skin disorders, in human subjects.

REFERENCES:
patent: 625159 (1899-05-01), Einhorn
patent: 3993679 (1976-11-01), Hall et al.
patent: 4036837 (1977-07-01), Sellsted et al.

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