Carbostyril substituted pyridazinones

Drug – bio-affecting and body treating compositions – Designated organic active ingredient containing – Heterocyclic carbon compounds containing a hetero ring...

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544238, A61K 3150

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active

051303140

ABSTRACT:
A pyridazinone compound represented by the general formula ##STR1## wherein Ar is ##STR2## in which R.sup.1, R.sup.2 and R.sup.3 may be identical or different, and each represents a hydrogen atom, a lower alkyl group, a trifluoromethyl group, a halogen atom, a cyano group or a nitro group, and R.sup.4 represents a hydrogen atom, a lower alkoxy group, or a lower alkyl group substituted by a lower alkoxy group or a carbamoyl group, and C* is an assymmetric carbon atom,
or a salt thereof. This compound is useful for the treatment of diseases of the circulatory system.

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Chem. Abstr vol. 112 entry 198402(e) (1990).
Slater et al., Journal Med. Chem., vol. 31 pp. 345-347 (1988).

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