Carbonylation of allylic alcohols and synthesis of an ambergris

Details Carbonylation of allylic alcohols and synthesis of an ambergris Carbonylation of allylic alcohols and synthesis of an ambergris

1990-10-09

1994-07-05

Ivy, C. Warren

Organic compounds -- part of the class 532-570 series

Organic compounds

Heterocyclic carbon compounds containing a hetero ring...

C07D30792

Patent

active

053268881

ABSTRACT:
A process for the carbonylation of allylic alcohols such as nerolidol, farnesol, or their monocyclic analogues with carbon monoxide at a pressure of at least 30 bar in the presence of a polar solvent and a palladium halide catalyst, optionally an alkali metal halide salt, and optionally an alcoholic solvent. The carbonylated product may then be reduced to the corresponding alcohol, which is cyclized in the presence of Lewis or Bronsted acids to afford an ambergris fragrance compound.

REFERENCES:
patent: 4681707 (1987-07-01), Alper et al.
patent: 5077417 (1991-12-01), Schulte-Elte et al.

Affiliated with

Also associated with

Rating

Carbonylation of allylic alcohols and synthesis of an ambergris does not yet have a rating. At this time, there are no reviews or comments for this patent.

If you have personal experience with Carbonylation of allylic alcohols and synthesis of an ambergris , we encourage you to share that experience with our LandOfFree.com community. Your opinion is very important and Carbonylation of allylic alcohols and synthesis of an ambergris will most certainly appreciate the feedback.

Rate now

Comments { 0 }

Profile ID: LFUS-PAI-O-797094