Chemistry: molecular biology and microbiology – Enzyme – proenzyme; compositions thereof; process for... – Isomerase
Patent
1979-08-06
1983-08-16
Shapiro, Lionel M.
Chemistry: molecular biology and microbiology
Enzyme , proenzyme; compositions thereof; process for...
Isomerase
435 94, 435 99, 435886, C12N 992, C12P 1924, C12P 1914, C12R 1465
Patent
active
043992226
ABSTRACT:
Acidophilic and acidoduric streptomycetes strains have been found to produce carbohydrases. These Streptomyces effectively elaborate glucose isomerase under acid conditions typically unfavorable for growth of conventional glucose isomerase producing Streptomyces. Sterilization of the culture and production media may be avoided by selectively propagating newly discovered Streptomyces acidodurans under acidic conditions which will effectively eliminate contaminating microorganisms. The Streptomyces acidodurans herein also have the ability to undergo cultivation and elaborate glucose isomerase over a relatively broad pH range. Constitutive streptomycetes strains have also been isolated. Glucose isomerases derived from these Streptomyces strains are particularly effective for isomerizing glucose syrups to fructose-containing syrups.
REFERENCES:
patent: 3826714 (1974-07-01), Suekane
patent: 4061539 (1977-12-01), Lee
Flowers et al.; in Microbios 1977, 20(80), 99-106.
Bok Song H.
Jackson LeRoy E.
Schroedel Cynthia J.
Seidman Martin
A. E. Staley Manufacturing Company
Hendrickson M. Paul
Meyerson Charles J.
Shapiro Lionel M.
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