Drug – bio-affecting and body treating compositions – Designated organic active ingredient containing – Having -c- – wherein x is chalcogen – bonded directly to...
Patent
1990-07-23
1992-03-31
Daus, Donald G.
Drug, bio-affecting and body treating compositions
Designated organic active ingredient containing
Having -c-, wherein x is chalcogen, bonded directly to...
544254, 544229, 544323, 544277, C07D47102, A61K 31505
Patent
active
051008963
ABSTRACT:
The present invention provides a compound of formula (I) ##STR1## and salts and solvates and pharmaceutically acceptable derivatives thereof, and describes processes for their preparation, pharmaceutical compositions containing them and their use in the treatment of viral diseases, especially those caused by the Herpetoviridae.
REFERENCES:
patent: 4138562 (1979-02-01), Vince
patent: 4268672 (1981-05-01), Vince
patent: 4543255 (1985-09-01), Shealy et al.
patent: 4605659 (1986-08-01), Verbeyden et al.
patent: 4714701 (1987-12-01), Beauchamp
patent: 4728736 (1988-03-01), Shealy et al.
patent: 4857531 (1989-08-01), Borthwick et al.
Shealy et al., "Synthesis and Antiviral Evaluation of Carbocyclic Analogues of 2-Amino-6-Substituted-Purine 3'-Deoxyribofuranosides", J. Med. Chem., vol. 30, No. 6, (1987) pp. 1090-1094.
Shealy et al., "Synthesis and Antiviral of Carbocyclic Analogues of 2'-Deoxyribofuranosides of 2-Amino-6-Substituted-Purines and of 2-Amino-6-Substituted-8-Azapurines", J. Med. Chem., vol. 27, No. 11, (1984) pp. 1416-1421.
Vince et al., "Synthesis and Antiviral Activity of Carbocyclic Analogues of Xylofuranosides of 2-Amino-6-Substituted-Purines and 2-Amino-6-Substituted-8-Azapurines", J. Med. Chem., vol. 30, No. 11, (1987) pp. 2026-2030.
Vince et al., "Synthesis and Anti-HIV Acitivity of Carbocyclic 2',3'-Didehydro-2',3'-Dideoxy 2,6-Disubstituted Purine Nucleosides", J. Med. Chem., vol. 33, No. 1, (1990) pp. 17-21.
Patterson and Vince, "Synthesis and Biological Evaluation of Carbocyclic Analogues of Lyxofuranosides of 2-Amino-6-Substituted-Purines and 2-Amino-6-Substituted-Purines and 2-Aminio-6-Substituted-8-Azapurines", J. Med. Chem., vol. 33, No. 4, (1990) pp. 1214-1219.
Shealy et al., "Synthesis and Antiviral Evaluation of Carbocyclic Analogues of Ribofuranosides of 2-Amino-6-Substituted-Purines and of 2-Amino-6-Substituted-8-Azapurines", J. Med. Chem., vol. 27, No. 5, (1984) pp. 670-674.
Shealy et al., "Carbocyclic Analogs of Guanosine and 8-Azaguanosine", J. Pharm. Sci., vol. 62, No. 9, (1973) pp. 1432-1434.
Lee et al., "Carbocyclic Analogs of Arabinosylpurine Nucleosides", J. Pharm. Sci., vol. 69, No. 9, (1980) pp. 1019-1021.
Vince et al., "Facile Synthesis of Carbocyclic Lyxo-and Ribonucleosides", J. Org. Chem., vol. 45, No. 3, (1980) pp. 531-533.
Shealy et al., "Cyclopentyl Derivatives of 8-Azahypoxanthine and 8-Azaadenine, Carbocyclic Analogs of 8-Azainosine and 8-Azaadenosine(1)", J. Het. Chem., vol. 10, No. 4, (1973) pp. 601-605.
Shealy et al., "Synthesis and Antiviral Activity of the Carbocyclic Analogues of 5-Ethyl-2'-Deoxyuridine and of 5-Ethynyl-2'-deoxyuridine", J. Med. Chem., vol. 29, No. 1, (1986) pp. 79-84.
Baxter Anthony D.
Biggadike Keith
Borthwick Alan D.
Kirk Barrie E.
Mo Chi L.
Daus Donald G.
Glaxo Group Limited
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