Chemistry: molecular biology and microbiology – Micro-organism – tissue cell culture or enzyme using process... – Preparing alpha or beta amino acid or substituted amino acid...
Reexamination Certificate
2007-11-20
2007-11-20
Nashed, Nashaat T. (Department: 1656)
Chemistry: molecular biology and microbiology
Micro-organism, tissue cell culture or enzyme using process...
Preparing alpha or beta amino acid or substituted amino acid...
C435S106000, C536S023200
Reexamination Certificate
active
11011701
ABSTRACT:
A DNA fragment which encodes a polypeptide defined in the following (a) or (b), and a polypeptide defined in the following (c) or (d):(a) a polypeptide which has at least the amino acid sequence of the amino acid numbers 50 to 393 in SEQ ID NO: 2 shown in Sequence Listing,(b) a polypeptide which has at least the amino acid sequence of the amino acid numbers 50 to 393 in SEQ ID NO: 2 shown in Sequence Listing including substitution, deletion, insertion, addition, or inversion of one or several amino acids, and can constitute a protein having a carbamoyl-phosphate synthetase activity with a large subunit of carbamoyl-phosphate synthetase having the amino acid sequence of SEQ ID NO: 3,(c) a polypeptide which has the amino acid sequence of SEQ ID NO: 3 shown in Sequence Listing,(d) a polypeptide which has the amino acid sequence of SEQ ID NO: 3 shown in Sequence Listing including substitution, deletion, insertion, addition, or inversion of one or several amino acids, and can constitute a protein having a carbamoyl-phosphate synthetase activity with a small subunit of carbamoyl-phosphate synthetase having the amino acid sequence of the amino acid numbers 50 to 393 in SEQ ID NO: 2.
REFERENCES:
patent: 6255086 (2001-07-01), Kuwabara et al.
patent: 2002/0090702 (2002-07-01), Kuwabara et al.
patent: 0 077 548 (1983-04-01), None
patent: 0 261 627 (1988-03-01), None
patent: 57-30476 (1982-06-01), None
patent: WO 95/03417 (1995-02-01), None
M. Crabeel, et al., Journal of Bacteriology, vol. 143, No. 2, pp. 921-925, “Use of Gene Cloning to Determine Polarity of an Operon: Genes Carab ofEscherichia coli”, Aug. 1980.
M. Mergeay, et al., Molec. Gen. Genet., pp. 299-316, “Physiology and Genetics of Carbamoylphosphate Synthesis inEscherichia coliK12”, 1974.
J. Piette, et al., Proc. Natl. Acad. Sci. USA, vol. 81, pp. 4134-4138, “DNA Sequence of the Cara Gene and the Control Region of Carab: Tandem Promoters, Prespectively Controlled by Arginine and the Pyrimidines, Regulate the Synthesis of Carbamoyl-Phosphate Synthetase inEscherichia coliK-12”, Jul. 1984.
H.Yang, et al., Eur. J. Biochem., vol. 249, pp. 443-449, “Cloning and Characterization of the Arginine-Specific Carbamoyl-Phosphate Synthetase FromBacillus stearotherophilus”, 1997.
M.Tuchman, et al., Applied and Enviromental Microbiology, vol. 63, No. 1, pp. 33-38, “Enhanced Production of Arginine and Urea by Genetically EngineeredEscherichia coliK-12 Strains”, Jan. 1997.
K.Matsui, et al., Agricultural and Biological Chemistry, vol. 51, No. 3, pp. 823-828, XP-001160768, “Cloning of Tryptophan Genes ofBrevibacterium lactofermentum, A Glutamic Acid-Producing Bacterium”, 1987.
J.P. Schofield, et al., Clinical Science, Biochemical Society and the Medical Research Society, vol. 84, No. 2, pp. 119-128, XP-002038834, “Molecular Studies on an Ancient Gene Encoding for Carbamoyl-Phosphate Synthetase”, Aug. 25, 1997.
F.S. Lawson, et al., Microbiology, vol. 141, pp. 1183-1191, XP-008020579, “Organization of Carbamoyl-Phosphate Synthetase Genes inNeisseria gonorrhoeaeIncludes a Large, Variable Intergenic Sequence Which is Also Present in Other Neisseria Species”, 1995.
A. Elagoz, et al., Gene an International Journal on Genes and Genomes, vol. 182, pp. 37-43, “Structure and Organisation of the Pyrimidine Biosynthesis Pathway Genes inLactobacillus plantarum: A PCR Strategy for Sequencing Without Cloning”, Dec. 1996.
M. Kilstrup, et al., Database Biosis, Biological Abstracts Inc., US, Biosis, 1 page, AN PREV198886113458, “Nucleotide Sequence of the Cara Gene and Regulation of the Carab Operon inSalmonella-typhimurium”, 1988 From Eurp. J. Biochem. (1988)176, 421-430 (abstract).
H. Yang, et al., Database Biosis, Biological Abstracts Inc., US, Biosis, 2 pages, AN PREV 199799812800, “Cloning and Characterization of the Arginine-Specific Carbamoyl-Phosphate Synthetase fromBacillus stearothermophilus”, 1997 From:Eurp. J. Biochem. (1997)249, 443-449 (abs.
Ghim, Sa0Youl, et al., “Molecular Characterization of Pyramidine Biosynthesis Genes From the Thermophile Bacillus Caldolyticus,” Microbiology, 140, 1994, pp. 479-491.
Elagoz, Aram, et al., “Structure and Organisation of the Pyrimidine Biosynthesis Pathway Genes in Lactobacillus Plantarum: A PCR Strategy for Sequencing Without Cloning,” Gene, 182, 1996, pp. 37-43.
Cole, S.T., et al., “Deciphering the Biology of Mycobacterium Tuberculosis from Complete Genome Sequence,” Nature, vol. 393, Jun. 11, 1998, pp. 537-544.
G. Deckert, et al., Carboamoyl Phosphate Synthetase Small Subunit, 1 page, The Complete Genome Of The Hyperthermophilic Bacterium Aquifex Aeolicus, Aug. 1, 1998, Database: EMBL, Accession No. 066727.
S. Tabata, Carbamoyl-phosphate Synthease, Pyrimidine-specific, Large Chain, 2 pages, “Sequence Analysis of the Genome of the Unicellular Cyanobacterium,” Nov. 1, 1996, Database EMBL, Accession No. Q55756.
Hashiguchi Ken-ichi
Ito Hisao
Kurahashi Osamu
Kuwabara Yoko
Mori Yukiko
Ajinomoto Co. Inc.
Nashed Nashaat T.
LandOfFree
Carbamoyl-phosphate synthetase gene of coryneform bacteria... does not yet have a rating. At this time, there are no reviews or comments for this patent.
If you have personal experience with Carbamoyl-phosphate synthetase gene of coryneform bacteria..., we encourage you to share that experience with our LandOfFree.com community. Your opinion is very important and Carbamoyl-phosphate synthetase gene of coryneform bacteria... will most certainly appreciate the feedback.
Profile ID: LFUS-PAI-O-3891064