Carbamate compounds containing thiocarbamoyl group and process f

Details Carbamate compounds containing thiocarbamoyl group and process f Carbamate compounds containing thiocarbamoyl group and process f

1996-01-03

1997-05-06

Richter, Johann

Organic compounds -- part of the class 532-570 series

Organic compounds

Esters having the thiocarboxylate group, -cx-, wherein the...

C07C33304

Patent

active

056273002

ABSTRACT:
There are disclosed 3-thiocarbamoyl-2-phenyl-1,3-propandiol carbamate racemate, represented by the following structural formula I: ##STR1## and its (R)- and (S)- optical isomers and intermediates thereof, which are very effective for prophylaxis and treatment of central nervous system disorders including epilepsy and apoplexy. 3-Thiocarbamoyl-2-phenyl-1,3-propandiol carbamate racemate and its (S)- and (R)- optical isomers are prepared from 2-phenyl-1,3-propandiol monothiocarbamate, (S)-2-phenyl-1,3-propandiol monothiocarbamate, and (S)-2-phenyl-1,3-propandiol monocarbamate, respectively.

REFERENCES:
patent: 2884444 (1959-04-01), Berger et al.
patent: 2901501 (1959-08-01), Wasson et al.
patent: 2937119 (1960-05-01), Berger et al.

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