Method and apparatus for preparing composite skin replacement

Chemistry: molecular biology and microbiology – Animal cell – per se ; composition thereof; process of... – Primate cell – per se

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435325, 435395, 435397, 435398, 424 937, 623 15, C12N 500, A61F 210

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active

059768789

ABSTRACT:
A method and apparatus for forming a permanent, composite skin replacement consisting of an epidermal component and a porous, resorbable, biosynthetic laminated dermal membrane component for use in wound repair. The dermal membrane is formed in the apparatus, which permits regulation of variables affecting membrane structure. The dermal membrane may be modified to incorporate biologically active molecules to enhance wound repair and to reduce infection when the skin replacement is applied to a wound.

REFERENCES:
patent: 4703108 (1987-10-01), Silver et al.
patent: 5282859 (1994-02-01), Eisenberg
Guesdon,et al.; The Journal of Histochemistry and Cytochemistry, vol. 27, No. 8, pp. 1131-1139; 1979.

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