Capillary electrophoresis buffer

Details Capillary electrophoresis buffer Capillary electrophoresis buffer

1991-08-30

1993-11-09

Niebling, John

Chemistry: electrical and wave energy

Processes and products

Electrostatic field or electrical discharge

204299R, G01N 2726, G01N 27447

Patent

active

052599396

ABSTRACT:
Disclosed herein is a dynamic coating buffer useful in the analysis of samples by open-tube capillary electrtophoretic methods using untreated fused silica capillary columns. The dynamic coating buffer comprises at least one agent having at least two dissociation constants, and high ionic strength characteristics, said agent having a molarity range of from about 0.2M and about 1.0M and a pH range of from between about 3.0 and 11.0. A particularly preferred dynamic coating buffer comprises 0.5M sodium phosphate.

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patent: 5089103 (1992-02-01), Swedberg
patent: 5120413 (1992-06-01), Chen et al.
Sally A. Swedberg "Characterization of Protein Behavior in High-Performance Capillary Electrophoresis Using a Novel Capillary System" Analytical Biochemistry 185, 51-56.
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Abstract--Accession No. 54-10B00091, J. Chromatogr., 559(1-2), 18 Oct. 1991, Salomon, K., et al: "Evaluation of fundamental properties of a silica capillary used for capillary electrophoresis", pp. 69-80.
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