Canine COX-2 proteins and uses thereof

Details Canine COX-2 proteins and uses thereof Canine COX-2 proteins and uses thereof

2009-01-12

2010-02-23

Pak, Yong D (Department: 1652)

Chemistry: molecular biology and microbiology

Enzyme , proenzyme; compositions thereof; process for...

Oxidoreductase

C435S004000, C435S006120, C435S025000, C435S069100, C435S071100, C435S252300, C435S320100, C435S440000, C536S023100, C536S023200

Reexamination Certificate

active

07666641

ABSTRACT:
The present invention relates to canine COX-1 and COX-2 proteins; to canine COX-1 and COX-2 nucleic acid molecules, including those that encode such COX-1 and COX-2 proteins, respectively; to antibodies raised against such proteins; and to compounds that inhibit the activity of such proteins. The present invention also includes methods to obtain such proteins, nucleic acid molecules, antibodies, and inhibitory compounds. The present invention also includes therapeutic compositions comprising such inhibitory compounds, particularly those that specifically inhibit COX-2 activity, as well as the use of such therapeutic compositions to treat animals.

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