Canine and feline B7-2 nucleic acid molecules and uses thereof

Details Canine and feline B7-2 nucleic acid molecules and uses thereof Canine and feline B7-2 nucleic acid molecules and uses thereof

2005-02-08

2005-02-08

Gambel, Phillip (Department: 1644)

Organic compounds -- part of the class 532-570 series

Organic compounds

Carbohydrates or derivatives

C536S023100, C514S04400A, C435S069100, C435S455000, C435S252300, C435S320100

Reexamination Certificate

active

06852847

ABSTRACT:
The present invention relates to canine and feline B7 proteins; to B7 nucleic acid molecules, including those that encode such B7 proteins; to antibodies raised against such B7 proteins; and to therapeutic compounds that regulate B7 function. The present invention also includes methods to identify and obtain such proteins, nucleic acid molecules, antibodies, and inhibitory compounds. Also included in the present invention are therapeutic compositions comprising such proteins, nucleic acid molecules, antibodies and/or inhibitory compounds as well as the use of such therapeutic compositions to regulate an immune response in an animal.

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Hash, S.M.Cloning, Sequencing, Expression and Characterization of the Feline CD28/CD80 Accessory Signaling Complex. Dissertation, Veterinary Microbiology, Texas A&M University, May, 1997.
Yang, S. et al. “Cloning of Genes Encoding Canine Co-Stimulatory Molecules” Annual Meeting of the Professional Research Scientists on Experimental Biology, part II, San Francisco, USA, Apr. 18-22, 1998.FASEB Journal for Experimental Biology12(5):a940, No. 5444 (Mar. 1998).

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