Calcium bis...

Details Calcium bis... Calcium bis...

2006-04-18

2010-10-19

Kosack, Joseph R (Department: 1626)

Drug, bio-affecting and body treating compositions

Designated organic active ingredient containing

Ester doai

C558S410000

Reexamination Certificate

active

07816405

ABSTRACT:
The present invention relates to calcium bis[(2S)-3-[3-[(2S)-3-(4-chloro-2-cyanophenoxy) -2-fluoropropoxy]phenyl]-2-isopropoxypropionate] represented by formula (I), a hydrate thereof, a crystal of the compound of formula (I), and a crystal of the hydrate of the compound of formula (I) which are useful as pharmaceuticals, and to processes for producing the same, and intermediates therefore, and processes for production thereof.There is need for (2S)-3-[3-[(2S)-3-(4 -chloro-2-cyanophenoxy)-2-fluoropropoxy]phenyl]-2-isopropoxypropionic acid, in the form of a drug substance, purified so as to minimize a residual solvent content and having a uniformized specification and a highly favorable workability, and a process for producing the same.Crystalline calcium bis[(2S)-3-[3-[(2S)-3-(4 -chloro-2-cyanophenoxy)-2-fluoropropoxy]phenyl]-2-isopropoxypropionate], a calcium salt of (2S) -3-[3-[(2S)-3-(4-chloro-2-cyanophenoxy)-2-fluoropropoxy]phenyl]-2-isopropoxypropionic acid, solves the above problem.

REFERENCES:
patent: 4895873 (1990-01-01), Schafer
patent: 7056942 (2006-06-01), Hildesheim et al.
patent: 7521461 (2009-04-01), Li
patent: 2004/0102634 (2004-05-01), Matsuura et al.
patent: 10020275 (2001-10-01), None
patent: 0 271 586 (1988-06-01), None
patent: 63-313746 (1988-12-01), None
patent: 3-17054 (1991-01-01), None
patent: 4-334339 (1992-11-01), None
patent: 6-239788 (1994-08-01), None
patent: 2000-281626 (2000-10-01), None
patent: 2003-520835 (2003-07-01), None
patent: 2004-18378 (2004-01-01), None
patent: 2004-517891 (2004-06-01), None
patent: WO-87/07603 (1987-12-01), None
patent: WO-00/53566 (2000-09-01), None
patent: WO-01/55078 (2001-08-01), None
patent: WO-02/057251 (2002-07-01), None
patent: WO 02/100812 (2002-12-01), None
patent: WO-02/100812 (2002-12-01), None
patent: WO-03/106024 (2003-12-01), None

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