Butenyl substituted taxanes

Organic compounds -- part of the class 532-570 series – Organic compounds – Heterocyclic carbon compounds containing a hetero ring...

Reexamination Certificate

Rate now

  [ 0.00 ] – not rated yet Voters 0   Comments 0

Details

C514S449000, C549S214000, C549S511000, C560S160000

Reexamination Certificate

active

06872842

ABSTRACT:
Taxane derivatives having a 3′ butenyl substituted C13 side chain.

REFERENCES:
patent: 4923857 (1990-05-01), Murata et al.
patent: 5015744 (1991-05-01), Holton
patent: 5081237 (1992-01-01), Murata et al.
patent: 5136060 (1992-08-01), Holton
patent: 5175315 (1992-12-01), Holton
patent: 5229526 (1993-07-01), Holton
patent: 5254580 (1993-10-01), Chen et al.
patent: 5254703 (1993-10-01), Holton
patent: 5272171 (1993-12-01), Ueda et al.
patent: 5274124 (1993-12-01), Holton
patent: 5284864 (1994-02-01), Holton et al.
patent: 5294637 (1994-03-01), Chen et al.
patent: 5336785 (1994-08-01), Holton
patent: 5338872 (1994-08-01), Holton et al.
patent: 5384399 (1995-01-01), Holton
patent: 5399726 (1995-03-01), Holton et al.
patent: 5405972 (1995-04-01), Holton et al.
patent: 5430160 (1995-07-01), Holton
patent: 5466834 (1995-11-01), Holton
patent: 5478854 (1995-12-01), Farina et al.
patent: 5532363 (1996-07-01), Holton
patent: 5539103 (1996-07-01), Holton
patent: 5574156 (1996-11-01), Holton
patent: 5637732 (1997-06-01), Holton et al.
patent: 5646176 (1997-07-01), Golik et al.
patent: 5723634 (1998-03-01), Holton
patent: 5728850 (1998-03-01), Holton et al.
patent: 5808102 (1998-09-01), Poss et al.
patent: 5973160 (1999-10-01), Poss et al.
patent: 6005120 (1999-12-01), Holton et al.
patent: 6005138 (1999-12-01), Holton et al.
patent: 6069260 (2000-05-01), Holton
patent: 0 400 971 (1990-12-01), None
patent: 0 428 376 (1991-05-01), None
patent: 0 558 959 (1993-09-01), None
patent: 0 568 203 (1993-11-01), None
patent: 0 577 082 (1994-01-01), None
patent: 0 582 469 (1994-02-01), None
patent: 0 590 267 (1994-04-01), None
patent: 0 605 637 (1994-07-01), None
patent: 0 605 638 (1994-07-01), None
patent: WO 9010443 (1990-09-01), None
Denis et al. “A Highly Efficient, Practical Approach To Natural Taxol”, J. Am. Chem. Soc., (1988), pp. 5917-5919, vol. 110, No. 17.
Holton et al., “A Synthesis of Taxusin”, J. Am. Chem. Soc., (1988), pp. 6558-6560, 110.
Senilh et al., “Chime Organique Biologique—Hemisynthese de nouveaux analogues du taxol. Etude de leur interaction avec la tubuline”, C.R. Acad. Sc. Paris, t. 299, Serie II. (1984), pp. 1039-1043, No. 15.
Magri et al., “Modified Taxols, 4. Synthesis and Biological Activity of Taxols Modified in the Side-Chain”, Journal of Natural Products, (1988), pp. 298-306, vol. 51, No. 2.
Samaranayake et al., “Modified Taxols. 5.1 Reaction of Taxol With Electrophilic Reagents and Preparation of a Rearranged Taxol Derivative with Tubulin Assembly Activity”, J. Org. Chem., (1991), pp. 5114-5119, vol. 56, No. 17.
Ojima et al., “New and Efficient Approaches to the Semisynthesis of Taxol and Its C-13 Side-chain Analogs by Means of β-Lactam Synthon Method”, Tetrahedron, (1992), pp. 6985-7012, vol. 48, No. 34.
Borman, S., Science-Technology, “New Family of Taxol, Taxotere Analogs Developed”, Chem. & Engineering News, (1993), pp. 36-37.
Wani et al., “Plant Antitumor Agents. VI. The Isolation and Structure of Taxol, a Novel Antileukemic and Antitumor Agent from Taxus Brevifolia”, J. Am. CHem, Soc., (1971), pp. 2325-2327, vol. 93, No. 9.
Deutsch et al., “Synthesis of Congeners and Prodrugs. 3. Water-Soluble Prodrugs of Taxol with Potent Antitumor Activity”, Journal of Medicinal Chem., (Apr, 1989), pp. 788-792, vol. 32, No. 4.
Kaiser et al., “Synthesis of Esters of Acid-Unstable Alcohols by Means of n-Butyllithium”, J. Org. Chem., (1970), pp. 1198-1199, vol. 35, No. 1.
Holton, R.A., “Synthesis of the Taxane Ring System”, JACS, (1984), pp. 5731-5732 (1984), vol. 106.
International Search Report from EP 02 019 283 dated Sep. 9, 2002.

LandOfFree

Say what you really think

Search LandOfFree.com for the USA inventors and patents. Rate them and share your experience with other people.

Rating

Butenyl substituted taxanes does not yet have a rating. At this time, there are no reviews or comments for this patent.

If you have personal experience with Butenyl substituted taxanes, we encourage you to share that experience with our LandOfFree.com community. Your opinion is very important and Butenyl substituted taxanes will most certainly appreciate the feedback.

Rate now

     

Profile ID: LFUS-PAI-O-3435392

  Search
All data on this website is collected from public sources. Our data reflects the most accurate information available at the time of publication.