Branched amides of L-aspartyl-d-amino acid dipeptides

Details Branched amides of L-aspartyl-d-amino acid dipeptides Branched amides of L-aspartyl-d-amino acid dipeptides

1980-11-05

1983-10-25

Kepplinger, Esther M.

Food or edible material: processes, compositions, and products

Products per se, or processes of preparing or treating...

Noncarbohydrate sweetener or composition containing same

426590, 426591, 426660, 426576, 426565, 426656, 426804, 2601125R, A23L 1236

Patent

active

044119259

ABSTRACT:
Amides of L-aspartyl-D-amino acid dipeptides of the formula ##STR1## and physiologically acceptable cationic and acid addition salts thereof wherein R.sup.a is methyl, ethyl, n-propyl or isopropyl; R is a branched member selected from the group consisting of fenchyl, diisopropylcarbinyl, d-methyl-t-butylcarbinyl, d-ethyl-t-butylcarbinyl, di-t-butylcarbinyl, 2-methylthio-2,4-dimethylpentan-3-yl, ##STR2## said amides are potent sweeteners having advantages over the prior art, edible compositions containing them, methods for their use in edible compositions and novel amine and amide intermediates useful in their production.

REFERENCES:
patent: 3907766 (1975-09-01), Fujino et al.
patent: 3959245 (1976-05-01), Nakajima et al.
patent: 3971822 (1976-07-01), Chibata et al.
Beck, Symposium:Sweeteners, The AVI Publishing Co., Inc., Westport, Conn., 131, 136 and 137 (1974).
Ariyoshi et al., Bull. Chem. Soc., Japan, 47, 326 (1974).
Fujino et al., Chem. Pharm. Bull. 24, 2112 (1976).
Myoshi et al., Bull. Chem. Soc., Japan, 51, 1443 (1978).

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