Bradykinin antagonists

Details Bradykinin antagonists Bradykinin antagonists

1994-08-29

1999-01-26

Achutamurthy, Ponnathapura

Drug, bio-affecting and body treating compositions

Designated organic active ingredient containing

Peptide containing doai

530314, 530328, 530345, 530402, 930DIG813, 930800, A61K 3808, C07K 718

Patent

active

058638997

ABSTRACT:
A bradykinin antagonist of the formula:

REFERENCES:
patent: 4618598 (1986-10-01), Conn
patent: 4894443 (1990-01-01), Greenfield et al.
Kodama et al, European Journal of Pharmacology, vol. 151, pp. 317-320 (1988).
Vavmek et al, J. Peroc. 8.sup.th Am. Pept. Sump., pp. 381-384, (1983).
Cheronis et al, J. of Medicinal Chemistry, vol. 35, pp. 1563-1572, (1992).
Stewart et al, Adv. Exp. Med. Biol., Kinias-3, Pt. A, pp. 585-589, (1983).
Carr, "The Effect of Anti-Inflammatory Durgs on Increased Vascular Permeability Induced by Chemical Mediators," The Journal of Pathology, vol. 108 (1), (1972) pp. 1-14.
Calixto et al, "Nonpeptide Bradykinin Antagonists", (1991), pp. 97-129.
Cheronis et al, "Bradykinin Antagonists: Synthesis and in vitro Activity of Bissuccinimidoalkane Peptide Dimers" Recent Progress on Kinins, (1992) pp. 551-558.

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